Difference between revisions of "Host invasion by microorganisms"

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=[[Parasites - WikiBlood|Parasites]]=
 
=[[Parasites - WikiBlood|Parasites]]=
  
==Types==
 
Parasites broadly include:
 
*Helminths (worms)
 
*Arthropods (insects)
 
*Protozoa (single-celled eukaryotes)
 
 
==Immunity to Parasites==
 
The immune system relies on granulocytes ([[Mast Cells - WikiBlood|mast cells]] and [[Eosinophils - WikiBlood|eosinophils]]) and the production of [[Immunoglobulin E - WikiBlood|IgE]] antibody to combat parasitic infection.  Once produced in response to danger signals, IgE attaches to circulating granulocytes.  IgE then binds to the parasite, signals mast cell and eosinophil degranulation, and causes enzymatic digestion of the intruder.
 
  
 
=References=
 
=References=
 
*<div id="Janeway">{{citation|initiallast = Murphy|initialfirst = K|2last = Travers|2first = P|finallast = Walport|finalfirst = M|year = 2008|title = Janeway's Immunobiology|ed = 7th |city = New York|pub = Garland Science Publishing}}</div>
 
*<div id="Janeway">{{citation|initiallast = Murphy|initialfirst = K|2last = Travers|2first = P|finallast = Walport|finalfirst = M|year = 2008|title = Janeway's Immunobiology|ed = 7th |city = New York|pub = Garland Science Publishing}}</div>

Revision as of 17:00, 2 September 2008

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IMMUNOLOGY


Introduction

One of the main causes of disease is infection by microorganisms, with four types so far identified:

  • Viruses
  • Bacteria
  • Fungi
  • Parasites- comprising protozoa and helminths

All exist as either:

  • Primary pathogens (obligate): presence always corresponds with disease
  • Secondary (opportunistic): prerequisites must be fulfilled before disease occurs

Microorganisms can enter the body by three routes:

  • Contact: typically seen in dermatological infections
  • Aerosol: typically respiratory infections
  • Orofecal:typically enteric infections


Viruses

Bacteria

Parasites

References

  • Murphy, K., Travers, P. and Walport, M. (2008) Janeway's Immunobiology. 7th ed. New York: Garland Science Publishing.