Difference between revisions of "Immunoglobulin D"
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<p>''Shortened to IgD''</p> | <p>''Shortened to IgD''</p> | ||
| − | [[Image:LH IgD.png|thumb| | + | |
| − | [[Image:IgD.jpg|thumb|right| | + | [[Image:LH IgD.png|thumb|250px|right|'''IgD''']] |
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| + | [[Image:IgD.jpg|thumb|right|250px|IgD - B. Catchpole, RVC 2008]] | ||
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| + | ==Overview== | ||
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| + | IgD is present in ruminants, pigs, dogs and rodents but has not been identified in horses, cats, rabbits and chickens. It is mainly expressed on the surface of B-cells i.e. it is never secreted. | ||
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==Structure== | ==Structure== | ||
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| + | IgD is Y-shaped. In rodents, it has two heavy chain constant regions, whereas other mammals have three. IgD has a long hinge region and no disulfide bonds. | ||
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==Function== | ==Function== | ||
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| − | + | IgD is only expressed in association with [[IgM]]. It is important in B-cell development. | |
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<center><b><sup>[[Immunoglobulins|Immunoglobulins]]: [[Immunoglobulin A|Immunoglobulin A]], [[Immunoglobulin D|Immunoglobulin D]], [[Immunoglobulin E|Immunoglobulin E]], [[Immunoglobulin G|Immunoglobulin G]] & [[Immunoglobulin M|Immunoglobulin M]]</sup></b></center> | <center><b><sup>[[Immunoglobulins|Immunoglobulins]]: [[Immunoglobulin A|Immunoglobulin A]], [[Immunoglobulin D|Immunoglobulin D]], [[Immunoglobulin E|Immunoglobulin E]], [[Immunoglobulin G|Immunoglobulin G]] & [[Immunoglobulin M|Immunoglobulin M]]</sup></b></center> | ||
Revision as of 14:37, 9 January 2011
Shortened to IgD
Overview
IgD is present in ruminants, pigs, dogs and rodents but has not been identified in horses, cats, rabbits and chickens. It is mainly expressed on the surface of B-cells i.e. it is never secreted.
Structure
IgD is Y-shaped. In rodents, it has two heavy chain constant regions, whereas other mammals have three. IgD has a long hinge region and no disulfide bonds.
Function
IgD is only expressed in association with IgM. It is important in B-cell development.