Changes

====Infectious Necrotic Hepatitis (Black Disease)====

====Infectious Necrotic Hepatitis (Black Disease)====

*''Clostridium novyi'' type B

*[[Clostridium novyi|''Clostridium novyi'' type B]]

*grazing animals

*grazing animals

**mainly sheep, also cattle (and reported sometimes in horses and goats)

**mainly sheep, also cattle (and reported sometimes in horses and goats)

*organism is widely distributed within the soil and normally present in GIT and [[Liver - Anatomy & Physiology|liver]] of grazing animals on infected pastures

*organism is widely distributed within the soil and normally present in GIT and [[Liver - Anatomy & Physiology|liver]] of grazing animals on infected pastures

**worldwide

**worldwide

*it is ingested by the animal and spores are absorbed via the gut and travel to the [[Liver - Anatomy & Physiology|liver]] , where they lie dormant in [[Macrophages - WikiBlood|macrophages (Kupffer cells)]] - also found in [[Bone Marrow - Anatomy & Physiology|bone marrow]] and [[Spleen - Anatomy & Physiology|spleen]]

*it is ingested by the animal and spores are absorbed via the gut and travel to the [[Liver - Anatomy & Physiology|liver]] , where they lie dormant in [[Macrophages|macrophages (Kupffer cells)]] - also found in [[Bone Marrow - Anatomy & Physiology|bone marrow]] and [[Spleen - Anatomy & Physiology|spleen]]

*seasonal disease associated with Fasciola [[Liver - Anatomy & Physiology|liver]] flukes

*seasonal disease associated with Fasciola [[Liver - Anatomy & Physiology|liver]] flukes

**migrating immature [[Liver - Anatomy & Physiology|liver]] flukes precipitate the disease

**migrating immature [[Liver - Anatomy & Physiology|liver]] flukes precipitate the disease

*[[Liver - Anatomy & Physiology|liver]] fluke control

*[[Liver - Anatomy & Physiology|liver]] fluke control

*remove dead carcasses from pasture

*remove dead carcasses from pasture

[[Category:Hepatitis,_Bacterial]]

[[Category:Hepatitis,_Bacterial]]