Difference between revisions of "Liver Pigmentation"
Jump to navigation
Jump to search
(New page: {{toplink |backcolour =BCED91 |linkpage =Alimentary System - Pathology |linktext =Alimentary System |maplink = Alimentary System (Content Map) - Pathology |pagetype =Pathology |sublink1=Li...) |
|||
| Line 9: | Line 9: | ||
}} | }} | ||
<br> | <br> | ||
| + | ==Congenital melanosis== | ||
| + | *in calves and lambs | ||
| + | *black discoloration of small irregular portions of the [[Liver - Anatomy & Physiology|liver]] | ||
| + | |||
| + | |||
| + | ==Haemosiderin== | ||
| + | *in chronic passive congestion and surrounding areas where there has been prior necrosis and haemorrhage | ||
| + | *found within the Kuppfer cells | ||
| + | *use Perls' stain | ||
| + | |||
| + | ==Lipofuscin== | ||
| + | *an insoluble golden brown pigment which occurs within hepatocytes | ||
| + | *use Schmorl's stain - dark blue | ||
| + | *increases with age - called the ''''senility' pigment''' | ||
| + | *it is commonly seen in hepatocytes near to the centrilobular vein in older cats | ||
| + | *no clinical significance | ||
| + | |||
| + | ==Bile== | ||
| + | *especially prominent in obstructive jaundice | ||
| + | *discolours the tissues green | ||
| + | *intrahepatic bile canaliculi are distended with a greenish pigment - called '''bile plugs''' | ||
| + | *larger foci are seen in long standing cases when the hepatocytes rupture: the discharged bile is then surrounded by macrophages and perhaps giant cells - called '''bile lakes''' | ||
| + | *use Fouchet stain - green | ||
Revision as of 12:31, 21 August 2008
|
Congenital melanosis
- in calves and lambs
- black discoloration of small irregular portions of the liver
Haemosiderin
- in chronic passive congestion and surrounding areas where there has been prior necrosis and haemorrhage
- found within the Kuppfer cells
- use Perls' stain
Lipofuscin
- an insoluble golden brown pigment which occurs within hepatocytes
- use Schmorl's stain - dark blue
- increases with age - called the 'senility' pigment
- it is commonly seen in hepatocytes near to the centrilobular vein in older cats
- no clinical significance
Bile
- especially prominent in obstructive jaundice
- discolours the tissues green
- intrahepatic bile canaliculi are distended with a greenish pigment - called bile plugs
- larger foci are seen in long standing cases when the hepatocytes rupture: the discharged bile is then surrounded by macrophages and perhaps giant cells - called bile lakes
- use Fouchet stain - green