Difference between revisions of "Rabbit Haemorrhatic Disease Virus"
Jump to navigation
Jump to search
m (Text replace - "Category:To_Do_-_Viruses" to "Category:To_Do_-_Clinical/Viruses") |
|||
| Line 33: | Line 33: | ||
*Vaccination now exists and has proven effective | *Vaccination now exists and has proven effective | ||
**Inactivated whole virus or recombinant capsid protein | **Inactivated whole virus or recombinant capsid protein | ||
| − | [[Category:Caliciviridae]][[Category:Rabbit]] | + | [[Category:Caliciviridae]][[Category:Rabbit Viruses]] |
[[Category:To_Do_-_Clinical/Viruses]] | [[Category:To_Do_-_Clinical/Viruses]] | ||
Revision as of 10:43, 5 August 2010
 |
This article is still under construction. |
Antigenicity
- Single serotype
- Related to European Brown Hare Syndrome Virus
Hosts
- Rabbits
- Hares seroconvert without disease
Pathogenesis
- High and rapid mortality (within 2 days of contraction)
- Systemic disease, including:
- Hemorrhage
- Generalized congestion, especially in the lungs and trachea
- Liver necrosis
- Clinical signs:
- Depression
- Anorexia
- Muscular tremors and incoordination
Epidemiology
- Infection of domestic rabbits occurs through contact with wild rabbits
- First described in China in 1984
- Reported in Europe since 1992, though current opinion holds a less pathogenic variant to be circulating in the wild population, affording some protection
Diagnosis
- Post-mortem lesions include hepatic necrosis and enlargement of the spleen
- Serology may be performed (ELISA and PCR)
Control
- Until 1996, RHDV was notifiable and slaughter was indicated
- Vaccination now exists and has proven effective
- Inactivated whole virus or recombinant capsid protein