Severe Combined Deficiency - Laboratory Examples

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Athymic Nude Mouse - Armin Kübelbeck 2008
  • Severe Combined Immune Deficiency(SCID)
  • Athymic nude mice (no thymus)
    • No functional T cells
    • Cell-mediated immunodeficiency
  • Knock-out mice
    • E.g. Gene coding for CD4, CD8, IL-10 removed
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