Uraemia

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Lesions due to uraemia associated with pyelonephritis/chronic renal failure (Courtesy of Alun Williams (RVC))
  • In terminal renal failure animal may present with painful ulcers in mouth, which become secondarily infected with Fusiformis.
    • High concentrations of toxic materials in the blood results in degeneration of small arterioles.
  • In the mouth, this damage to the blood supply can cause epithelial necrosis.
  • Usually seen as erosions along the ventrolateral borders of the tongue and on the cheeks, especially opposite the teeth.
  • In some cases there may be more extensive necrosis which may involve subepithelial tissue
    • for example, the tip of the tongue may slough.
  • Most commonly seen in dog sometimes in cat.