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{{review}}
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=Immune-mediated uveitis/recurrent uveitis=
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==Introduction==
 
==Introduction==
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Uveitis is a very important disease. It can be secondary to keratitis, but is common as a primary immune-mediated disorder. The
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Immune-mediated uveitis/recurrent uveitis/uveitis is a very important disease. It can be secondary to keratitis, but is common as a primary immune-mediated disorder. The
 
major problem is its tendency to recur, causing progressive loss of vision. This is the most common cause of blindness.
 
major problem is its tendency to recur, causing progressive loss of vision. This is the most common cause of blindness.
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==Diagnosis==
 
==Diagnosis==
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* If diagnosis is attempted, then '''routine blood tests''' should be run along with '''titres for [[Spirochaetes#Leptospira|leptospirosis]] and [[Brucella species|brucellosis]], [[Equine Herpesvirus 1|equine herpes virus]], [[Streptococci#Strangles|strangles]] and [[Donkey - Equine Viral Arteritis|equine viral arteritis]].  
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* If diagnosis is attempted, then '''routine blood tests''' should be run along with '''titres for [[:Category:Leptospiraceae|leptospirosis]] and [[:Category:Brucella species|brucellosis]], [[Equine Herpesvirus 1|equine herpes virus]], [[Strangles|strangles]] and [[Equine Viral Arteritis - Donkey|equine viral arteritis]].  
 
* '''Conjunctival biopsy''' will diagnose the presence of ''Onchocerca''
 
* '''Conjunctival biopsy''' will diagnose the presence of ''Onchocerca''
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* Topical '''atropine drops''' (1-2%) should be applied hourly until mydriasis occurs and then twice daily until the acute inflammatory response has subsided, possibly for up to two weeks. Monitor for gut function as long-term atropine slows gut movement
 
* Topical '''atropine drops''' (1-2%) should be applied hourly until mydriasis occurs and then twice daily until the acute inflammatory response has subsided, possibly for up to two weeks. Monitor for gut function as long-term atropine slows gut movement
 
* '''Cyclosporin''' 2% is an ocular immunomodulator, which can produce excellent results but only in about 50% of cases. It can be used to replace corticosteroids if corneal ulceration is present. A ten-day course given at twelve-hourly intervals is recommended
 
* '''Cyclosporin''' 2% is an ocular immunomodulator, which can produce excellent results but only in about 50% of cases. It can be used to replace corticosteroids if corneal ulceration is present. A ten-day course given at twelve-hourly intervals is recommended
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==Literature Search==
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[[File:CABI logo.jpg|left|90px]]
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Use these links to find recent scientific publications via CAB Abstracts (log in required unless accessing from a subscribing organisation).
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<br><br><br>
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[http://www.cabdirect.org/search.html?q=title%3A%28uveitis%29+AND+%28od%3A%28horses%29+OR+od%3A%28donkeys%29%29 Uveitis in horses or donkeys publications]
    
==References==
 
==References==
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* Svendsen, E.D., Duncan, J. and Hadrill, D. (2008) ''The Professional Handbook of the Donkey'', 4th edition, Whittet Books
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* Grove, V. (2008) Conditions of the eye In Svendsen, E.D., Duncan, J. and Hadrill, D. (2008) ''The Professional Handbook of the Donkey'', 4th edition, Whittet Books, Chapter 11
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|linkpage =Uveal Tract Diseases - Donkey
 
|linkpage =Uveal Tract Diseases - Donkey
 
|linktext =Uveal Tract Diseases - Donkey
 
|linktext =Uveal Tract Diseases - Donkey
|rspace={{Donkey}}
   
|pagetype=Donkey
 
|pagetype=Donkey
 
}}
 
}}
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{{infotable
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|Maintitle = [[Sponsors#The Donkey Sanctuary|This section was sponsored and content provided by '''THE DONKEY SANCTUARY''']]
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|Maintitlebackcolour = B4CDCD
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}}
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[[Category:Donkey]]
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[[Category:Uveal Tract Diseases - Donkey]]
Author, Donkey, Bureaucrats, Administrators
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