Clostridium perfringens type A

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  • Gas gangrene and myositis
    • Extensive bacterial invasion of damaged muscle
    • Gas production causing subcutaneous crepitus
    • Similar manifestations as malignant oedema
  • Necrotising enterocolitis in pigs and necrotic enteritis in chickens (alpha toxin with lecithinase activity)
  • Canine haemorrhagic gastroenteritis (cytotoxic enterotoxin)
  • Typhlocolotis in horses, possibly associated with Colitis X