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''Clostridium difficle'' is a gram positive bacteria of the family ''Clostridiaceae''.  They are normally part of the normal flora, so known as a commensal bacteria.  The problem arises when the bacteria competing within the host are destroyed by antibiotics. 
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''C. difficle'' become overpopulated, and begin to produce pathogenic strains producing toxins, namely enterotoxin and cytotoxin.  These may cause diarrhoea, and abdominal pains, or pseudomembranous colitis (PMC) under more severe circumstances.
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*Dogs with chronic diarrhoea
 
*Dogs with chronic diarrhoea
 
*New born foals with haemorrhagic enterocolitis
 
*New born foals with haemorrhagic enterocolitis
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