Changes

Also known as '''''BLAD'''''  

Also known as '''''BLAD'''''  

Affected calves will appear normal at birth but then become clinically ill within the first few weeks. Life expectancy is generally not more than one year old.

Affected calves will appear normal at birth but then become clinically ill within the first few weeks. Life expectancy is generally not more than one year old.

== Clinical Signs ==

== Clinical Signs ==

Chronic recurrent infections such as pneumonia, diarrhoea, dermatitis, gingivitis or vasculitis. The infection will always reappear, even following antibiotic doses usually high enough to cure the infection.

Chronic recurrent infections such as pneumonia, diarrhoea, dermatitis, gingivitis or vasculitis. The infection will always reappear, even following antibiotic doses usually high enough to cure the infection.

== Diagnosis ==

== Diagnosis ==

There are tests available in the US to diagnose heterozygous carriers and homozygous calves.

There are tests available in the US to diagnose heterozygous carriers and homozygous calves.

== Control ==

== Control ==

Test the herd and eliminate carrier animals.

Test the herd and eliminate carrier animals.

== Literature Search ==

== Literature Search ==

<br> Use these links to find recent scientific publications via CAB Abstracts (log in required unless accessing from a subscribing organisation). <br><br><br> [http://www.cabi.org/cabdirect/FullTextPDF/2010/20103049446.pdf '''Bovine leukocyte adhesion deficiency syndrome (BLAD): a recessive disorder in Holstein Friesian cattle - a review.''' Vijay Kumar; Ashwani Sharma; Agricultural Research Communication Centre, Karnal, India, Agricultural Reviews, 2009, 30, 4, pp 293-300, many ref. - '''Full Text Article''']  

<br> Use these links to find recent scientific publications via CAB Abstracts (log in required unless accessing from a subscribing organisation). <br><br><br> [http://www.cabi.org/cabdirect/FullTextPDF/2010/20103049446.pdf '''Bovine leukocyte adhesion deficiency syndrome (BLAD): a recessive disorder in Holstein Friesian cattle - a review.''' Vijay Kumar; Ashwani Sharma; Agricultural Research Communication Centre, Karnal, India, Agricultural Reviews, 2009, 30, 4, pp 293-300, many ref. - '''Full Text Article''']  

== References ==

== References ==

 

 

[[Category:Primary_Innate_Immunity_Deficiencies]] [[Category:Lymphoreticular_and_Haematopoietic_Diseases_-_Cattle]] [[Category:Expert_Review - Farm Animal]]

[[Category:Primary_Innate_Immunity_Deficiencies]] [[Category:Lymphoreticular_and_Haematopoietic_Diseases_-_Cattle]] [[Category:Expert_Review - Farm Animal]]