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[[Image:LH B cells Peyers Patch Histology.jpg|right|thumb|250px|<p>'''B Cells in Lymph node'''</p><sup>©RVC 2008</sup>]]
B cells have B cell receptors (BCR), or antigen binding sites. This is [[IgM]] when the B cell is immature, changing to [[IgD]] when the cell is mature. B cells also express MHC II, CD9, CD,19, CD20 and CD24.</p>
<p>Under antigenic stimulation they differentiate into [[B cell differentiation#Plasma cells|plasma cells]] and [[B cell differentiation#Memory cells|memory cells]].</p>
B-cells also act as Antigen-Presenting Cells (APCs) by presenting digested fragments to T-cells on [[MHC - WikiBlood#MHC II|MHC II]].
Also known as '''''B lymphocytes'''''
So named as they were initially found in the [[Bursa of Fabricius - Anatomy & Physiology|Bursa of Fabricius]], B cells produce antibodies and are associated with '''humoral immunity''' (T cells are part of the cell-mediated immune response), and are an integral part of the [[:Category:Adaptive Immune System|'''adaptive immune system''']]. They represent 20-30% of circulating lymphocytes.
[[Category:Lymphocytes|C]]
B cells have cell surface proteins known as B cell receptors (BCRs) that are known as [[Immunoglobulins - Overview|immunoglobulins]]; [[IgM]] is the membrane bound BCR that is expressed when the B cell is immature, changing to [[IgD]] when the cell is mature. IgM has a large molecular mass and can bind up to 10 antigens simultaneously. B cells also express MHC II, CD9, CD,19, CD20 and CD24.
<p>Under antigenic stimulation B cells [[B cell differentiation|'''differentiate''']] into [[B cell differentiation#Plasma cells|plasma cells]] and [[B cell differentiation#Memory cells|memory cells]].</p>
B-cells also act as Antigen-Presenting Cells (APCs) by presenting digested fragments to [[T cells]] on [[Major Histocompatability Complexes#MHC II|MHC II]].
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{{Jim Bee 2007}}
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[[Category:Lymphocytes|B]]