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| == Introduction == | | == Introduction == |
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| Subclinical reinfections are important in spreading disease and more than 70% of cattle in the UK have antibodies to BRSV. | | Subclinical reinfections are important in spreading disease and more than 70% of cattle in the UK have antibodies to BRSV. |
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| + | == Classification == |
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| + | BRSV's Baltimore Classification is V, ssRNA negative sense virus, and is a part of the Orthopneumovirus genus. It is an enveloped virus, utilizing fusion proteins to facilitate cellular fusion and syncytium formation. |
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| == Signalment == | | == Signalment == |
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| It can cause disease in adult cattle too however, it is more severe in young stock. | | It can cause disease in adult cattle too however, it is more severe in young stock. |
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| == Clinical Signs == | | == Clinical Signs == |
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| Clinical signs include [[Pulmonary Emphysema|emphysema]] and [[Pulmonary Oedema|oedema]]. In adult cattle, you may see a drop in milk yield. | | Clinical signs include [[Pulmonary Emphysema|emphysema]] and [[Pulmonary Oedema|oedema]]. In adult cattle, you may see a drop in milk yield. |
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| == Diagnosis == | | == Diagnosis == |
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| Antigen detection by '''immunocytochemistry''' for intracytoplasmic viral inclusions containing labelled viral protein can also be performed as well as serology. A 4-fold rise in ELISA antibody in paired serum samples from several animals is indicative of the disease. | | Antigen detection by '''immunocytochemistry''' for intracytoplasmic viral inclusions containing labelled viral protein can also be performed as well as serology. A 4-fold rise in ELISA antibody in paired serum samples from several animals is indicative of the disease. |
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| == Treatment and Control == | | == Treatment and Control == |
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| Treatment with antibiotics is often used to treat secondary infections and lessen clinical signs and help the body focus on eliminating the virus. | | Treatment with antibiotics is often used to treat secondary infections and lessen clinical signs and help the body focus on eliminating the virus. |
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− | It is important to try to improve husbandry as in [[Bovine Parainfluenza - 3 (PI-3)#Secondary_Concerns|PI-3]] in order to prevent the disease from occurring. Avoiding mixing of different aged calves is very important in the control of the disease, as is good hygiene. | + | It is important to try to improve husbandry as in [[Bovine Parainfluenza - 3#Treatment and Control|PI-3]] in order to prevent the disease from occurring. Avoiding mixing of different aged calves is very important in the control of the disease, as is good hygiene. |
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− | [[Vaccines]] are available but not effective as need to stimulate [[Lymphocytes#Cytotoxic_CD8.2B|cytotoxic T-cells]].
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| + | [[Vaccines]] are available but not effective as need to stimulate [[T cells#Cytotoxic_CD8.2B|cytotoxic T-cells]]. |
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| == References == | | == References == |
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| [[Category:Pneumovirinae]] [[Category:Cattle_Viruses]] [[Category:Expert_Review - Farm Animal]] [[Category:Respiratory_Viral_Infections]] | | [[Category:Pneumovirinae]] [[Category:Cattle_Viruses]] [[Category:Expert_Review - Farm Animal]] [[Category:Respiratory_Viral_Infections]] |
| [[Category:Respiratory Diseases - Cattle]] | | [[Category:Respiratory Diseases - Cattle]] |