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*In some primates it acts as a [[Primary Lymphoid Tissue - Anatomy & Physiology|primary lymphoid organ]]
 
*In some primates it acts as a [[Primary Lymphoid Tissue - Anatomy & Physiology|primary lymphoid organ]]
 
*Bone marrow is also a [[Secondary Lymphoid Tissue - Anatomy & Physiology|secondary lympoid tissue]]
 
*Bone marrow is also a [[Secondary Lymphoid Tissue - Anatomy & Physiology|secondary lympoid tissue]]
**By mass the largest
   
<p>It has little involvement in the primary immune response, but the migration of [[B cell differentiation - WikiBlood#Memory cells|memory cells]] into the marrow from the [[Spleen - Anatomy & Physiology|spleen]] and [[Lymph Nodes - Anatomy & Physiology|lymph nodes]] means that during a subsequent exposure to an antigen it produces significant amounts of antibodies.</p>
 
<p>It has little involvement in the primary immune response, but the migration of [[B cell differentiation - WikiBlood#Memory cells|memory cells]] into the marrow from the [[Spleen - Anatomy & Physiology|spleen]] and [[Lymph Nodes - Anatomy & Physiology|lymph nodes]] means that during a subsequent exposure to an antigen it produces significant amounts of antibodies.</p>
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===Others===
 
===Others===
 
*It is a significant source of antibodies as a large population of antibody-producing cells ([[B cell differentiation - WikiBlood#Plasma cells|plasma cells]]) reside in the bone marrow
 
*It is a significant source of antibodies as a large population of antibody-producing cells ([[B cell differentiation - WikiBlood#Plasma cells|plasma cells]]) reside in the bone marrow
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