Difference between revisions of "Grass Sickness"
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==Description== | ==Description== | ||
| − | Equine grass sickness, or equine dysautonomia causes a paralysis of the gastro-intestinal tract, by disruption of the autonomic nervous system. | + | Equine grass sickness, or equine dysautonomia causes a paralysis of the gastro-intestinal tract, by disruption of the autonomic nervous system. The condition may occur acutely, or progress chronically over several weeks, but is fatal in all cases. |
==Signalment== | ==Signalment== | ||
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*Reduced faecal output | *Reduced faecal output | ||
*Hypersalivation | *Hypersalivation | ||
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| − | + | ===Biopsy=== | |
| + | A definitive diagnosis is obtained by taking an ileal biopsy, and inspecting the intrinsic myenteric plexus. Degenerative lesions are seen in the autonomic nerve ganglia, | ||
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===Pathology=== | ===Pathology=== | ||
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*** ''[[Clostridium botulinum]]'' is thought to be involved. | *** ''[[Clostridium botulinum]]'' is thought to be involved. | ||
* A similar condition seen in hares | * A similar condition seen in hares | ||
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** At post mortem look for degenerative changes in coeliaco-mesenteric ganglia - need to examine histologically. | ** At post mortem look for degenerative changes in coeliaco-mesenteric ganglia - need to examine histologically. | ||
*** Ganglia are peanut sized and found in perirenal fat between adrenal gland and the aorta. | *** Ganglia are peanut sized and found in perirenal fat between adrenal gland and the aorta. | ||
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==Treatment== | ==Treatment== | ||
| − | + | There is no effective treatment, prompt euthanasia is indicated in acute and per acute cases, some chronic cases can be managed with intensive nursing care for a limited time period. | |
==Prognosis== | ==Prognosis== | ||
Revision as of 15:44, 23 July 2010
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This article is still under construction. |
Description
Equine grass sickness, or equine dysautonomia causes a paralysis of the gastro-intestinal tract, by disruption of the autonomic nervous system. The condition may occur acutely, or progress chronically over several weeks, but is fatal in all cases.
Signalment
Cases of Grass sickness are restricted to Northwestern Europe and South America with the highest incidence in the UK, in some parts of Eastern Scotland 1% of horses die annualy from the disease. Young animals, 2-7 years old are predisposed. The disease occurs in warm wet weather with peak incidences in spring and autumn. Affected horses usually live at pasture, those that have moved pasture within the preceeding two months are also at greater risk. In many cases the disease appears to be related to specific pstures or fields with a history of grass sickness affected horses, however it has been reported in animals with none of the usual risk factors.
Diagnosis
Clinical signs
- Depression
- Abdominal pain, episodes of colic
- Abdominal distension
- Dysphagia
- Inappetence
- Muscular tremors
- Reduced faecal output
- Hypersalivation
Biopsy
A definitive diagnosis is obtained by taking an ileal biopsy, and inspecting the intrinsic myenteric plexus. Degenerative lesions are seen in the autonomic nerve ganglia,
Pathology
- Stomach and small intestine large amounts of contain watery yellow fluid.
- There is an abrupt change in the large intestine, where no fluid is present.
- large intestine has very dry mucoid contents.
- There is an abrupt change in the large intestine, where no fluid is present.
- Stomach and small intestine large amounts of contain watery yellow fluid.
Pathogenesis
- Due to functional obstruction at ileocaecal valve and a degree of paralytic ileus of the small intestine.
- The exact cause is unknown, but a type of bacterial or fungal toxin which may damage autonomic nervous system ganglia may be involved.
- Clostridium botulinum is thought to be involved.
- A similar condition seen in hares
- At post mortem look for degenerative changes in coeliaco-mesenteric ganglia - need to examine histologically.
- Ganglia are peanut sized and found in perirenal fat between adrenal gland and the aorta.
- At post mortem look for degenerative changes in coeliaco-mesenteric ganglia - need to examine histologically.
Treatment
There is no effective treatment, prompt euthanasia is indicated in acute and per acute cases, some chronic cases can be managed with intensive nursing care for a limited time period.
Prognosis
The condition is fatal.
References
- Knottenbelt, D.C. A Handbook of Equine Medicine for Final Year Students University of Liverpool
- Rose, R. J. and Hodgson, D. R. (2000) Manual of Equine Practice (Second Edition) Sauders.
| Also known as: | Equine Dysautonomia |