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~~{{review}}~~

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~~{{toplink~~

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~~|backcolour = D1EEEE~~

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~~|linkpage =Cardiorespiratory System - Pathology~~

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~~|linktext =Cardiorespiratory System~~

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~~|maplink = Cardiorespiratory System (Content Map) - Pathology~~

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~~|pagetype =Pathology~~

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~~|sublink1=Lungs - Pathology~~

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~~|subtext1=LUNGS~~

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}}

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~~<br>~~

==Classification==

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*However, primary tumours are more common in dogs and cats than in other animals

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*Classification of pulmonary tumours can be difficult due to the [[~~General Pathology - Disorders of~~ Cell Growth#Metaplasia|metaplasia]] which can occur in both inflammation and in neoplasia

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*Classification of pulmonary tumours can be difficult due to the [[Cell Growth Disorders#Metaplasia|metaplasia]] which can occur in both inflammation and in neoplasia

**Bronchial papilloma

**Bronchial adenoma/ carcinoma (arising from major airways)

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===Sheep ~~pulmonary adenomatosis~~ (SPA/ Jaagsiekte)===

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===[[Sheep Pulmonary Adenomatosis]] (SPA/ Jaagsiekte)===

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*Also called '''pulmonary carcinomatosis'''

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*Infectious [[Bronchi and Bronchioles Inflammatory - Pathology#Infectious causes of bronchitis or bronchiolitis|bronchiolar]]-[[Lungs Inflammatory - Pathology#Infectious causes of pneumonia|alveolar]] carcinoma caused by a [[Retroviridae|retrovirus]]

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*Commonest under intensive management systems which favour aerosol transmission and close contact of disease

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*Behaves like chronic pneumonia

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*Takes months to years to express itself clinically as coughing and exercise intolerance

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*Gross pathology:

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**Heavy lungs which fail to collapse

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**The lesions progress from small firm grey/white nodular lesions to extensive confluent areas with replacement by neoplastic tissue

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**Cut surface oozes fluid

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**There is often coexistent infection present

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**Occasional metastases to bronchial and mediastinal lymph nodes can occur

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*Histopathology:

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**Widespread proliferation of alveolar (Type 2) and terminal bronchiolar epithelium, lining the alveoli and lower airways

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**Multiple neoplastic foci of cuboidal/columnar cells forming papillary projections into the lumen

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**Metastases of the same in the bronchial and mediastinal lymph nodes

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*There is no serological test, and diagnosis depends upon raising the animal by the hind limbs whereupon a clear fluid issues from the nose = "Wheelbarrow test"

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*'''[[Jaagsiekte - Pathology|More information]]'''

===Carcinoids===

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*Also called '''myoblastomas'''

*Mesenchymal origin

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*Occurs in [[~~Hindgut Fermenters~~ - Horse - Anatomy ~~& Physiology~~|horses]]

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*Occurs in [[Alimentary System - Horse Anatomy|horses]]

*Grossly:

**Multiple discrete of partially confluent nodules

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**Mammary carcinoma (dog and cat)

**Haemangiosarcomas

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**[[~~Bones Hyperplastic and Neoplastic - Pathology#~~Osteosarcoma ~~(OSA)~~|Osteosarcomas]]

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**[[Osteosarcoma|Osteosarcomas]]

**Uterine adenocarcinoma (cattle)

**Malignant melanoma (horse)

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*'''In horses'''

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**cranial mediastinal lymphosarcoma

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**cranial mediastinal [[lymphosarcoma]]

**pulmonary granular cell tumour

**malignant melanoma

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<big>A space occupying lesion in the canine lung may produce periosteal thickening of the long bone - [[~~Bones Hyperplastic and Neoplastic - Pathology#~~Hypertrophic ~~osteopathy~~|'''Hypertrophic Osteopathy''']]</big>

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<big>A space occupying lesion in the canine lung may produce periosteal thickening of the long bone - [[Hypertrophic Osteopathy|'''Hypertrophic Osteopathy''']]</big>

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==Test yourself with the Lungs Pathology Flashcards==

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[[Lungs_Flashcards_-_Pathology|Lungs Pathology Flashcards]]

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[[Category:Lungs - Pathology]]

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[[Category:Respiratory System - Hyperplastic/Neoplastic Pathology]]

Lwilkie

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Pulmonary Neoplasia (view source)

Revision as of 17:39, 8 November 2012