Difference between revisions of "Type II Hypersensitivity"
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Production of IgM or IgG to cell surface antigens or extracellular matrix proteins. | Production of IgM or IgG to cell surface antigens or extracellular matrix proteins. | ||
Revision as of 13:55, 26 August 2008
Production of IgM or IgG to cell surface antigens or extracellular matrix proteins.
"Neutralisation" blockade of receptors:
- Myasthenia gravis
Immunological attack on target cells, destroying them by:
1. Antibody dependent cell cytotoxicity (ADCC)
- Pemphigus vulgaris
- Bullous pemphigoid
2. Complement mediated lysis
- Self RBC antigen:
- Immune mediated haemolytic anaemia
- Foreign RBC:
- Blood transfusion reaction
- Haemolytic disease of new born (Rhesus disease in humans and neonatal isoerythrolysis in foals and kittens)
- RBC parasite:
- Feline infectious anaemia (Mycoplasma haemofelis)
3. Phagocytosis