Difference between revisions of "Peritonitis - Cats and Dogs"

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==Description==
 
==Description==
 
Peritonitis is defined as the inflammation of the peritoneum.  Peritonitis can be septic or non-septic.  Septic peritonitis results from free bacteria in the peritoneal cavity, caused by perforating injuries to the gastrointestnal tract due to foreign bodies, necrosis secondary to obstruction or intussusception.  Non-septic, also known as chemical peritonitis, may be the result of leakage of bile, urine or pancreatic enzymes.  However, non-septic peritonitis can cause septic peritonitis, for example cases where septic urine is present.
 
Peritonitis is defined as the inflammation of the peritoneum.  Peritonitis can be septic or non-septic.  Septic peritonitis results from free bacteria in the peritoneal cavity, caused by perforating injuries to the gastrointestnal tract due to foreign bodies, necrosis secondary to obstruction or intussusception.  Non-septic, also known as chemical peritonitis, may be the result of leakage of bile, urine or pancreatic enzymes.  However, non-septic peritonitis can cause septic peritonitis, for example cases where septic urine is present.
 +
  
 
==Diagnosis==
 
==Diagnosis==
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===Laboratory Tests===
 
===Laboratory Tests===
 
====Haematology====
 
====Haematology====
 
+
*Significant leucocytosis or leucopaenia
  
 
====Biochemistry====
 
====Biochemistry====
*Significan leucocytosis or leucopaenia
 
 
*Hypoglycaemia
 
*Hypoglycaemia
 
*Increased lactate concentration
 
*Increased lactate concentration
  
====Other Tests====
 
*Abdominal fluid collected for laboartory analysis via abdominocentesis.  The fluid should be stained for intracellular bacteria and assessed for:
 
**amylase and lipase for pancreatitis
 
**bile for biliary leak
 
**creatinine for urine
 
**glucose (2.8 mmol/l) and lactate (>5.5 mmol/l) for sepsis
 
  
 
===Diagnostic Imaging===
 
===Diagnostic Imaging===
Line 45: Line 39:
  
  
 +
===Histopathology===
 +
*Abdominal fluid collected for laboartory analysis via abdominocentesis.  The fluid should be stained for intracellular bacteria and assessed for:
 +
**amylase and lipase for pancreatitis
 +
**bile for biliary leak
 +
**creatinine for urine
 +
**glucose (2.8 mmol/l) and lactate (>5.5 mmol/l) for sepsis
 +
 +
==Treatment==
 +
It is vital to identify cases which require emergency surgical intervention.  Any of the following is a major indication:
 +
*positive for intracellular bacteria.
 +
*free gas visible in the abdominal radiograph.
 +
*presence of penetrating injuries in the abdomen.
  
===Histopathology===
+
===Fluid therapy===
 +
*Aggressive fluid therapy with crystalloid and colloid should be given on initial presentation to improve haemodynamic parameter.
 +
*Fluid therapy is also very important in the postoperative period.
  
 +
===Analgesia===
 +
*Opiods should be given.
  
==Treatment==
+
===Antimicrobial===
*It is vital to identify cases which require emergency surgical intervention.  Any of the following is a major indication:
+
*Broad spectrum antibiotics should be given, preferably following culture and sensitivity test.
**positive for intracellular bacteria.
 
**free gas visible in the abdominal radiograph.
 
**presence of penetrating injuries in the abdomen.
 
  
  

Revision as of 15:37, 18 August 2009



Category:WikiClinical CanineCow
Category:WikiClinical FelineCow


Signalment

Description

Peritonitis is defined as the inflammation of the peritoneum. Peritonitis can be septic or non-septic. Septic peritonitis results from free bacteria in the peritoneal cavity, caused by perforating injuries to the gastrointestnal tract due to foreign bodies, necrosis secondary to obstruction or intussusception. Non-septic, also known as chemical peritonitis, may be the result of leakage of bile, urine or pancreatic enzymes. However, non-septic peritonitis can cause septic peritonitis, for example cases where septic urine is present.


Diagnosis

Clinical Signs

  • Depressed
  • Tachycardia
  • Tachypnoea
  • Pale, cyanotic or muddly mucous membranes
  • Hypothermia or hyperthermia
  • Abdominal pain


Laboratory Tests

Haematology

  • Significant leucocytosis or leucopaenia

Biochemistry

  • Hypoglycaemia
  • Increased lactate concentration


Diagnostic Imaging

Radiography

  • Abdominal radiography may reveal free gas in the abdomen. This is highly suggestive of peritonitis
  • Thoracic radiograph should be assessed for signs of metastatic disease.


Histopathology

  • Abdominal fluid collected for laboartory analysis via abdominocentesis. The fluid should be stained for intracellular bacteria and assessed for:
    • amylase and lipase for pancreatitis
    • bile for biliary leak
    • creatinine for urine
    • glucose (2.8 mmol/l) and lactate (>5.5 mmol/l) for sepsis

Treatment

It is vital to identify cases which require emergency surgical intervention. Any of the following is a major indication:

  • positive for intracellular bacteria.
  • free gas visible in the abdominal radiograph.
  • presence of penetrating injuries in the abdomen.

Fluid therapy

  • Aggressive fluid therapy with crystalloid and colloid should be given on initial presentation to improve haemodynamic parameter.
  • Fluid therapy is also very important in the postoperative period.

Analgesia

  • Opiods should be given.

Antimicrobial

  • Broad spectrum antibiotics should be given, preferably following culture and sensitivity test.


Prognosis

References

  • Ettinger, S.J. and Feldman, E. C. (2000) Textbook of Veterinary Internal Medicine Diseases of the Dog and Cat Volume 2 (Fifth Edition) W.B. Saunders Company.
  • Hall, E.J, Simpson, J.W. and Williams, D.A. (2005) BSAVA Manual of Canine and Feline Gastroenterology (2nd Edition) BSAVA
  • Nelson, R.W. and Couto, C.G. (2009) Small Animal Internal Medicine (Fourth Edition) Mosby Elsevier.