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Local Anaesthetics (view source)

Revision as of 20:53, 26 February 2009

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→‎Side Effects and Contraindications

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==Side Effects and Contraindications==

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Local anaesthetics may have undesirable effects on the CNS. These include termors, convulsions and respiratory depression. The cardiovasular system may also be adversely affected, with drug administration leasing to reduced cardiac contractility, vasodilation and hypotension. [[#Bupivicaine]] is particularly cardiotoxic, but stereoisomerism exists. The cardio- and neuro-toxic effects of dextrobupivicaine are greatly increased compared to that of levobupivicaine. Commercially available preparations of [[#Bupivicaine|bupivicaine]] are a 50:50 mixture of the two forms of the drug.

==Drugs in this Group==

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