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<p>To migrate through connective tissue they release proteases and glycoaminoglycanases.</p>
 
<p>To migrate through connective tissue they release proteases and glycoaminoglycanases.</p>
 
===Role in pathology===
 
===Role in pathology===
<p>Macrophages are seen in both [[Acute Inflammation - Pathology|acute]] and [[Chronic Inflammation - Pathology| chronic inflammation]].</p>  If large numbers of macrophages are found in chronic inflammatory processes, it implies the inability to eliminate the causal organism  e.g. [[Respiratory Bacterial Infections - Pathology#Tuberculosis|Tuberculosis]], [[:Category:Actinobacillus species|''Actinobacilllus'']], fungi, parasites and foreign bodies.
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<p>Macrophages are seen in both [[Acute Inflammation|acute]] and [[Chronic Inflammation - Pathology| chronic inflammation]].</p>  If large numbers of macrophages are found in chronic inflammatory processes, it implies the inability to eliminate the causal organism  e.g. [[Respiratory Bacterial Infections - Pathology#Tuberculosis|Tuberculosis]], [[:Category:Actinobacillus species|''Actinobacilllus'']], fungi, parasites and foreign bodies.
 
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