906
edits
Changes
no edit summary
==Pathogenesis==
==Pathogenesis==
Various aetiologies for the condition have been suggested. It has been widely proposed that telangiectasis occurs due to ischaemic necrosis of the liver relating to a number underlying causes. These include pregnancy, abdominal tympany and bacterial infection with ''Fusobacterium necrophorum''. Other theories include a neoplastic or immune-mediated process.
Various aetiologies for the condition have been suggested. It has been widely proposed that telangiectasis occurs due to ischaemic necrosis of the liver relating to a number underlying causes. These include thromboembolism, pregnancy, abdominal tympany and bacterial infection with ''Fusobacterium necrophorum''. Other theories include high levels of vitamin A, metabolic disturbances and neoplastic or immune-mediated processes.
Following slaughter, animals with mildly affected livers may be passed for food following trimming but severely affected carcasses must be condemned.
Following slaughter, animals with mildly affected livers may be passed for food following trimming but severely affected carcasses must be condemned.
==Pathology==
==Pathology==
Lesions usually appear as irregularly-shaped red depressions on the surface of the liver that extend into the parenchyma. They consist of dilated sinusoids filled with blood and lined with epithelium. On histopathology, hepatocytes appear swollen and degenerate with intracytoplasmic vacuoles and dilated sinusoids.
Lesions commonly develop at the parietal portion of the liver or at the periphery. They uually appear as irregularly-shaped red depressions on the surface of the liver that extend into the parenchyma. They consist of dilated sinusoids filled with blood and lined with epithelium. Livers containing a few lesions are commonly seen in young animals.
On histopathology, hepatocytes appear swollen and degenerate with intracytoplasmic vacuoles and dilated sinusoids. The dilated sinusoids are filled with erythrocytes and occasionally fibrin strands and leucocytes. The hepatic parenchyma surrounding the lesions is frequently normal.
==References==
==References==