| Question
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Answer
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Article
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| What are immunoglobulins also known as?
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Link to Answer Article
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| How many domains does the heavy chain have?
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- 1 variable domain
- 3 or 4 constant domains
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Link to Answer Article
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| How many domains does the light chain have?
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- 1 variable domain
- 1 constant domain
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Link to Answer Article
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| What are hypervariable domains?
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- Folded pockets of the variable domain into which antibody can bind
- Different antibodies have different amino acid sequences within the three varibale domains
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Link to Answer Article
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| What does Fab stand for and from which chain is it generated?
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- Fragment associated with antigen binding
- Light chain
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Link to Answer Article
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| What does Fc stand for and from which chain is it generated?
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- Constant fragment
- Heavy chain
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Link to Answer Article
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| What does the Fc fragment do?
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- Mediates phagocytosis
- Triggers inflammation
- Targets Ig to certain tissues
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Link to Answer Article
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| What are the four major effects of antibodies?
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- Blockage and agglutination
- Promotion of phagocytosis
- Degranulation of mast cells/eosinophils
- Complement Fixation
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Link to Answer Article
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