Difference between revisions of "Feline Asthma Syndrome"

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*Synonym: feline allergic bronchitis
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{{unfinished}}
*Pathology very similar to COPD/SPA-RAO in horses and human asthma, although few published papers relating to it
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*Allergens - house dust mites, fungal spores
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{| cellpadding="10" cellspacing="0" border="1"
*Widespread narrowing of airways
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| Also known as:
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| '''Feline Allergic Bronchitis'''
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|}
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==Description==
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Feline asthma is an allergic airway disease that bears many similarities with asthma in humans and with [[Recurrent Airway Obstruction|recurrent airway obstruction]] (RAO) in horses.  Affected animals become allergic to allergens present in their immediate environment, including house dust mites and fungal spores and produce [[IgE]] antibodies against these molecules.  When later exposed to the same allergens, asthmatic cats suffer a form of type I hypersensitivity response localised in the bronchi and bronchioles and resulting in constriction of the airways.
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Cases of feline asthma may be divided into '''intrinsic''' and '''extrinsic''' disease. 
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**'''Extrinsic asthma'''
 
**'''Extrinsic asthma'''
 
***Type I hypersensitivity in response to allergen challenge - mediated by [[IgE]]
 
***Type I hypersensitivity in response to allergen challenge - mediated by [[IgE]]
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**'''Intrinsic asthma'''
 
**'''Intrinsic asthma'''
 
***A proportion of cats there is an increased propensity for the bronchial smooth muscle to contract (increased bronchial reactivity) -> airway constriction
 
***A proportion of cats there is an increased propensity for the bronchial smooth muscle to contract (increased bronchial reactivity) -> airway constriction
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==Signalment==
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==Diagnosis==
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===Clinical Signs===
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===Laboratory Tests===
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===Diagnostic Imaging===
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==Treatment==
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==Prognosis==
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==References==
  
 
[[Category:Allergic Respiratory Diseases]][[Category:Cat]][[Category:To Do - James]]
 
[[Category:Allergic Respiratory Diseases]][[Category:Cat]][[Category:To Do - James]]

Revision as of 20:51, 1 September 2010



Also known as: Feline Allergic Bronchitis

Description

Feline asthma is an allergic airway disease that bears many similarities with asthma in humans and with recurrent airway obstruction (RAO) in horses. Affected animals become allergic to allergens present in their immediate environment, including house dust mites and fungal spores and produce IgE antibodies against these molecules. When later exposed to the same allergens, asthmatic cats suffer a form of type I hypersensitivity response localised in the bronchi and bronchioles and resulting in constriction of the airways.

Cases of feline asthma may be divided into intrinsic and extrinsic disease.

    • Extrinsic asthma
      • Type I hypersensitivity in response to allergen challenge - mediated by IgE
      • Pathological changes:
        • Exudate into airways - mucus/ cells
        • Thickened airway walls - oedema, glandular and smooth muscle hypertrophy, vascular congestion
        • Altered fluidity of mucus (associated with goblet cell hyperplasia) -> less effective mucociliary apparatus
    • Intrinsic asthma
      • A proportion of cats there is an increased propensity for the bronchial smooth muscle to contract (increased bronchial reactivity) -> airway constriction

Signalment

Diagnosis

Clinical Signs

Laboratory Tests

Diagnostic Imaging

Treatment

Prognosis

References