Difference between revisions of "Gastric Ulceration - Pig"

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(Created page with 'Gastric Ulceration - all species * Gastic ulceration is quite common in the pig- May be seen in 50-60% of pigs arriving at slaughterhouses. * Has serious economic consequence…')
 
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Revision as of 22:54, 28 June 2010

Gastric Ulceration - all species

  • Gastic ulceration is quite common in the pig- May be seen in 50-60% of pigs arriving at slaughterhouses.
  • Has serious economic consequences.
  • Clinical
    • Occasionally a well-grown pig will drop dead.
      • Deep ulcers have eroded into a blood vessel, causing massive haemorrhage into the stomach from and producing death very rapidly.
    • If long standing ulcers do not result in death, they do produce pain and discomfort.
      • Give low growth rate and poor feed conversion.
  • Pathogenesis
    • Gastric ulceration is associated with modern pig rearing, but the exact cause is unknown.
    • Causes are associated with gastric hyperacidity, and gastric ulceration is probably a multifactorial disease.
    • The following are suggested as possible causes:
      • Infection, e.g. Candida albicans, Streptococci, Staphylococci and mixes of these.
      • Copper toxicity- this is probably more significant.
        • Pigs are fed copper as growth promoter; 50 ppm is know to be toxic, and animals are often fed 250 ppm.
      • Vitamin E / Selenium deficiency.
      • Feeding on concrete floors.
        • Sand is licked up whe pigs eat.
      • Feeding finely milled cereal.
      • Stress
      • Possibly genetic factors.
  • Pathology
    • Most commonly affects pars oesophagea (squamous or non-glandular portion).
    • Starts with hyperkeratosis in the stratum corneum
      • Appears rough and thickened
      • May stop at this stage.
    • In approximately 30% of animals, the lesion starts to erode and quite deep ulcers may develop.
    • In a significant small number ,very deep ulcers develop and may affect virtually all of pars oesophagea.
    • Histologically, ulcers are large and flask-shaped ulcer with fibrin, necrosis, erosion and fibrosis at base.