Gastroprotective Drugs
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Antacids
These are administered orally and need frequent aministration when given to small animals. They work be chemically neutralising the acidic environment of the stomach. Examples are: magnesium carbonate, magnesium hydroxide, magnesium trisilicate, magnesium oxide, aluminium hydroxide and sodium bicarbonate.
Histamine (H2) Receptor Antagonists
Examples are cimetidine, ranitidine and famotidine. They can be administered orally or by injection and work by inhibiting the action of histamine on parietal cells. This results in reduced production of H+ ions and pepsin secretion.