Mesothelioma

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Peritoneal mesothelioma (Image sourced from BioMed Image Archive with permission)

Peritoneal

  • Mesotheliomas
    • Malignant - implantation rather than metastasis
    • Mainly cattle and dogs, occasionally in other species
    • Can be congenital in calves
    • Arise from serosa of pericardial, pleural and peritoneal cavities
    • Multiple small nodules, may be pedunculated, few milimeters to few centemeters, may present as villous projections
    • May be associated with milky or bloody effusions
    • Histologically usually appear similar to adenocarcinoma (papillary) or fibrosarcoma (spindle cells)

Image of glandular type mesothelioma in a cat from Cornell Veterinary Medicine

Pleural

  • Has been found in cat, dog, cow, goat and horse
  • Arise from pericardial, pleural and peritoneal surfaces
  • May be related to inhalation of asbestos
  • Grossly:
    • Multiple discrete nodules
  • Microscopically:
    • Can appear as a carcinoma or fibrosarcoma depending on which tissue, covering or supporting, is predominant in the neoplasm
  • Rarely metastasise but are considered malignant


Mesothelioma Learning Resources
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