Difference between revisions of "Porcine Stress Syndrome"

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[[Category:Muscles - Developmental Pathology]]
 
[[Category:Muscles - Developmental Pathology]]
[[Category:To Do - Jaimie Meagor]]
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[[Category:To Do - Steph]]

Revision as of 15:50, 1 July 2011

  • Malignant hyperthermia
  • Pigs, dogs, humans
  • Possibly a cellular defect resulting in high intacellular calcium ion concentration
    • -> Activates myofibrillar ATPase -> rapid intracellular glycolysis -> increase in body heat -> denature protein -> cell death -> leakage of cellular content -> oedema
  • Grossly:
    • Muscles are pale, soft and exudative
  • Histologically:
  • Inherited
  • Triggered by halothane anaesthesia, stress of handling, transportation or slaughter