View source for Villus atrophy with damage to crypts

* The primary insult is to crypt cells.
** Crypt cell death leads to dilated gland lumens (cysts).
** Production is impaired, eventually leading to insufficient cells for villi.  
* Enterocytes lost to lumen are replaced by increasingly immature cells.
** Gives rise to severe malabsorption.
* If damage is severe, erosions/ulcers may form which may eventually heal. 
** Even if there are no ulcers, damage can be long-term 
*** Causes long-term malabsorption.
* Examples include:
** '''Parvovirus'''
*** Target crypt cells.
** '''Lymphoma'''
*** Numerous neoplastic lymphocytes compress crypts.
** '''Cytotoxic chemicals'''
*** Dividing crypt cells are susceptible.

[[Category:Enteritis,_Villus_Atrophy]]
[[Category:To_Do_-_Clinical]]