View source for Small Animal Emergency and Critical Care Medicine Q&A 21

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'''This five-year-old, female Cocker Spaniel presented for evaluation of decreased appetite. PCV – 38%; TS – 6.8 gm/dl; ACT – 90 seconds; platelet count – 65,000/μl.'''

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<FlashCard questions="4">
|q1=What abnormality is seen here?
|a1=
Evidence of petechiae.
|l1=Platelet Abnormalities#Clinical Significance
|q2=Abnormalitites of which part of the coagulation system will result in these clinical signs?
|a2=
The presence of petechiae suggests the presence of either a vascular or platelet abnormality (vasculitis, thrombocytopenia, thrombopathia).
|l2=Thrombocytopaenia
|q3=Is the platelet count low enough to result in clinical signs of spontaneous hemorrhage?
|a3=
No. If the platelet count is less than 40,000/μl, the animal may have a bleeding tendency. 

Spontaneous hemorrhage, however, does not usually occur until the platelet count is less than 20,000/μl.
|l3=Thrombocytopaenia
|q4=Name four categories for the etiology of the coagulation abnormality. List one example for each cause.
|a4=
Causes of thrombocytopenia are: 
*decreased platelet production (myeloproliferative disease), 
*consumption (DIC), 
*sequestration (liver/spleen disease) 
*destruction (immune-mediated disease)
|l4=Thrombocytopaenia
</FlashCard>

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