Difference between revisions of "Adrenogenital Syndrome"

From WikiVet English
Jump to navigation Jump to search
 
(6 intermediate revisions by the same user not shown)
Line 1: Line 1:
{{toplink
 
|backcolour =EED2EE
 
|linkpage =Reproductive System - Anatomy & Physiology
 
|linktext =Reproductive System
 
|maplink = Reproductive System (Content Map) - Anatomy & Physiology
 
|sublink1=Reproductive System - Anatomy & Physiology#Fertilisation.2C Implantation and Early Embryonic Development
 
|subtext1=FERTILISATION , IMPLANTATION AND EARLY EMBRYONIC DEVELOPMENT
 
|sublink2=Fertilisation, Implantation and Early Embryonic Development -Sexual Differentiation- Anatomy & Physiology
 
|subtext2=SEXUAL DIFFERENTIATION
 
}}
 
<br>
 
 
== Aetiology ==
 
== Aetiology ==
  
Line 15: Line 4:
 
* Genotype is XX as should be female
 
* Genotype is XX as should be female
 
* Ovaries develop normally
 
* Ovaries develop normally
* Foetal [[Adrenal_Glands_-_Anatomy_%26_Physiology|Adrenal Gland]] is hyperactive and secretes large quantities of Adrenal Androgens, due to a '''21 hydroxylase mutation'''.
+
* Foetal [[Adrenal_Glands_- Anatomy & Physiology|Adrenal Gland]] is hyperactive and secretes large quantities of Adrenal Androgens, due to a '''21 hydroxylase mutation'''.
  
  
Line 33: Line 22:
  
  
[[Category:Reproductive System]]
+
[[Category:Reproductive Disorders]]
 +
[[Category:Reproductive Diseases - Dog]][[Category:Reproductive Diseases - Cat]]

Latest revision as of 14:25, 23 December 2010

Aetiology

  • Genotype is XX as should be female
  • Ovaries develop normally
  • Foetal Adrenal Gland is hyperactive and secretes large quantities of Adrenal Androgens, due to a 21 hydroxylase mutation.


Consequence

  • Wolffian Ducts persist due to the presence of Androgens, thus allowing development of male internal and external genitalia.
  • Mullarian Ducts persist due to the absence of testes, hence absence of Sertoli cell MIH secretion. This allows formation of female internal genitalia.


Morphology

  • Appears male with a micropenis and scrotum
  • Both male and female internal genitalia