| Line 1: |
Line 1: |
| − | ==[[Liver, Hydropic Degeneration]]== | + | {{frontpage |
| | + | |pagetitle =Liver - Degenerative Pathology |
| | + | |pagebody = |
| | + | |contenttitle =Content |
| | + | |contentbody =<big><b> |
| | | | |
| − | [[Hepatic Lipidosis]]
| + | <categorytree mode=pages>Liver - Degenerative Pathology</categorytree> |
| | | | |
| | + | </b></big> |
| | + | |logo =path-logo.png |
| | + | }} |
| | | | |
| − | ====Equine hyperlipidemia====
| |
| − | *fat pony syndrome
| |
| − | *occurs exclusively in fat ponies especially fat Shetland ponies
| |
| − | *more susceptible if pregnant and lactating
| |
| − | *may be triggered by some reduction in feed intake
| |
| − | *Clinical signs
| |
| − | **dullness
| |
| − | **colic
| |
| − | **anorexia
| |
| − | **hepatic encephalopathy
| |
| − | **mania (sometimes)
| |
| − | NB: similar to that in cats, as well as fatal (within a week)
| |
| | | | |
| − | ====Ovine White Liver Disease====
| |
| − | *Australia and Europe
| |
| − | *young lambs on lush pasture
| |
| − | *clinical signs
| |
| − | **ill thrift
| |
| − | **anorexia
| |
| − | **jaundice
| |
| − | **photosensitisation
| |
| − | *treatment
| |
| − | **responsive to Vitamin B12 and cobalt
| |
| − |
| |
| − | ===associated with derangement of carbohydrate metabolism===
| |
| − | ====[[DM|Diabetes mellitus]]====
| |
| − | *where there is insufficient insulin or a decrease in number of insulin receptors in cells
| |
| − | *seen mostly in dogs
| |
| − | *produces a markedly fatty [[Liver - Anatomy & Physiology|liver]] due to release of fat from the fat stores for use as an energy source
| |
| − | ====Ketosis====
| |
| − | *due to an excessive drain on carbohydrate stores because pregnant and lactating animals have a continuous demand for glucose
| |
| − | *ketosis results when fat metabolism which occurs in response to the increased energy demand is excessive
| |
| − | *ketone bodies accumulate in the blood and there is marked fatty change in the [[Liver - Anatomy & Physiology|liver]]
| |
| − | *can occur in starvation but commonly seen in two conditions in livestock:
| |
| − | =====ketosis of cattle (acetonemia)=====
| |
| − | *occurs in high yielding dairy cows a few weeks postpartum
| |
| − | *due to excessive loss of glucose in the milk
| |
| − | *milk yield drops
| |
| − | *smell of ketones on the breath
| |
| − | *ketones excreted in the milk
| |
| − | *self-limiting condition
| |
| − | =====pregnancy toxaemia in sheep=====
| |
| − | *occurs in ewes in late pregnancy carrying twin lambs ''''twin lamb disease''''
| |
| − | *drain of carbohydrate stores is due to rapidly growing foetuses
| |
| − | *serious condition and highly fatal
| |
| − | *clinical signs (neurological)
| |
| − | **apparent blindness
| |
| − | **dullness
| |
| − | **convulsions
| |
| − | **coma
| |
| − | *sequelae
| |
| − | **foetuses die
| |
| − | **apparent recovery in ewe until toxaemia from the decomposing foetuses results in the ewe's death
| |
| − |
| |
| − |
| |
| − | ===associated with anoxia and toxaemia===
| |
| − | ====anoxia====
| |
| − | *passive congestion
| |
| − | *anaemias
| |
| − | ====toxaemia====
| |
| − | *toxins absorbed from the gut interfere with many stages of triglyceride metabolism
| |
| | | | |
| | [[Category:Liver_-_Pathology]] | | [[Category:Liver_-_Pathology]] |