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| *Severe respiratory distress with laboured breathing and grunting on expiration | | *Severe respiratory distress with laboured breathing and grunting on expiration |
| *Can result in [[Diffuse Fibrosing Alveolitis|diffuse fibrosing alveolitis]] | | *Can result in [[Diffuse Fibrosing Alveolitis|diffuse fibrosing alveolitis]] |
− | *Gross appearance is that of enlarged wet lungs, the interlobular septa are markedly widenedith [[Lungs Circulatory - Pathology#Pulmonary oedema|oedema]] and [[Lungs Ventilation - Pathology#Emphysema|emphysema]] | + | *Gross appearance is that of enlarged wet lungs, the interlobular septa are markedly widenedith [[Pulmonary Oedema|oedema]] and [[Lungs Ventilation - Pathology#Emphysema|emphysema]] |
| *Underlying pathogenesis is ingestion of L-tryptophan in the pasture which is metabolised to 3-methylindole -> bloodstream -> lungs -> metabolised into a compound toxic to Type 1 pneumonocytes and non-ciliated bronchiolar epithelium | | *Underlying pathogenesis is ingestion of L-tryptophan in the pasture which is metabolised to 3-methylindole -> bloodstream -> lungs -> metabolised into a compound toxic to Type 1 pneumonocytes and non-ciliated bronchiolar epithelium |
| *Their loss allows massive flooding of the alveoli with a protein-rich fluid | | *Their loss allows massive flooding of the alveoli with a protein-rich fluid |
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| *Commonly found post mortem | | *Commonly found post mortem |
| *Can be a consequence of: | | *Can be a consequence of: |
− | # [[Lungs Circulatory - Pathology#Embolism, thrombosis and infarction|'''Septic emboli''']] lodging in the pulmonary vessels | + | # [[Pulmonary Embolism, Thrombosis and Infarction|'''Septic emboli''']] lodging in the pulmonary vessels |
| # '''Extension''' from severe focal suppurative [[Lungs Inflammatory - Pathology#Bronchopneumonia|bronchopneumonia]] | | # '''Extension''' from severe focal suppurative [[Lungs Inflammatory - Pathology#Bronchopneumonia|bronchopneumonia]] |
| # '''Aspiration''' of foreign material (see [[Lungs Inflammatory - Pathology#Aspiration pneumonia|aspiration pneumonia]]) | | # '''Aspiration''' of foreign material (see [[Lungs Inflammatory - Pathology#Aspiration pneumonia|aspiration pneumonia]]) |
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| ===Uraemic pneumonia=== | | ===Uraemic pneumonia=== |
− | *Severe uraemia causes increased permeability of the blood-air barrier and therefore can cause [[Lungs Circulatory - Pathology#Pulmonary oedema|pulmonary oedema]] | + | *Severe uraemia causes increased permeability of the blood-air barrier and therefore can cause [[Pulmonary Oedema|pulmonary oedema]] |
| *In addition to the oedema, there may also be degeneration and calcification of smooth muscle and connective tissue fibres | | *In addition to the oedema, there may also be degeneration and calcification of smooth muscle and connective tissue fibres |
| *Lungs do not collapse on opening the thorax in severe cases | | *Lungs do not collapse on opening the thorax in severe cases |