Seen most commonly in the cat. Elderly cats are affected with the average age of onset being 12-13 years.
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''Clinical signs'':
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*Weight loss despite polyphagia
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*Increased activity, nervousness (approximately 10% will show apathy)
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*Polyuria and polydipsia
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*Heat intolerance, panting
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*Tachycardia >240 bpm
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*Poor coat, matted and unkempt
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*Palpable thyroid mass often present
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Often see a [[Hypertrophic Cardiomyopathy|hypertrophic cardiomyopathy]] due to chronically increased heart rate and activity.
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[[Image:thyroid adenoma.jpg|right|thumb|125px|<small><center>'''Thyroid adenoma'''. Courtesy of T. Scase</center></small>]]
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''Aetiopathogenesis'':
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>98% are a functional adenoma of the thyroid gland and many will be palpable.
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''Treatment:''
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Surgical removal of the affected thyroid gland(s). If bilateral it is important to preserve at least one parathyroid gland to maintain calcium homeostasis.
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Medical treatment:
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*'''Carbamizole''': Interferes with thyroid hormone synthesis.
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*'''Radioactive iodine''' therapy. Useful for intrathoracic thyroid nodules.
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[[Category:To Do - Clinical]][[Category:Endocrine Diseases - Cat]]
[[Category:To Do - Clinical]][[Category:Endocrine Diseases - Cat]]