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Hyperparathyroidism (view source)

Revision as of 14:45, 21 February 2011

719 bytes removed ,  14:45, 21 February 2011
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* There are two common forms of secondary hyperparathyroisism:
 
* There are two common forms of secondary hyperparathyroisism:
 
*# [[Parathyroid Glands - Pathology#Nutritional Hyperparathyroidism|'''Nutritional Hyperparathyroidism''']]
 
*# [[Parathyroid Glands - Pathology#Nutritional Hyperparathyroidism|'''Nutritional Hyperparathyroidism''']]
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*#* This includes [[Parathyroid Glands - Pathology#Metabolic Bone Disease|Metabolic Bone Disease]].
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*#* This includes [[Metabolic Bone Disease]].
 
*# [[Parathyroid Glands - Pathology#Renal Hyperparathyroidism|'''Renal Hyperparathyroidism''']]
 
*# [[Parathyroid Glands - Pathology#Renal Hyperparathyroidism|'''Renal Hyperparathyroidism''']]
 
* Both forms result in increased osteoclastic resorption of bone and deposition of fibro-osteoid matrix that fails to mineralise.   
 
* Both forms result in increased osteoclastic resorption of bone and deposition of fibro-osteoid matrix that fails to mineralise.   
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** Osteoclastic resorption
 
** Osteoclastic resorption
 
** Fibrous replacement
 
** Fibrous replacement
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=====Metabolic Bone Disease=====
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=====[[Metabolic Bone Disease]]=====
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* Metabolic bone disease affects lizards in captivity, particularly young green iguanas
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* The condition is caused by:
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** Dietary deficiency of calcium and vitamin D
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*** For example, due to poor lighting (which diminishes viatmin D production).
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** Dietary excess of phosphorus
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** Certain toxicities
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** Diseases of the kidneys, [[Liver - Anatomy & Physiology|liver]] or parathyroid
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*** This aetiology is rare
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* Clinical signs include:
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** Lethargy
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** Inability to support weight
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** Rounded skull
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** Spontaneous fractures
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** Adult animals also show signs of [[Parathyroid Glands - Pathology#Hypocalcaemia|hypocalcaemia]]
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* The skeleton shows reduced density on radiography.
   
====Renal Hyperparathyroidism====
 
====Renal Hyperparathyroidism====
 
* Renal Hyerparathyroidism is mostly seen in the dog as an expression of chronic renal disease.
 
* Renal Hyerparathyroidism is mostly seen in the dog as an expression of chronic renal disease.
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