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| − | ===Acanthosis Nigricans===
| + | #REDIRECT[[:Category:Integumentary System - Pathology]] |
| − | *Occurs in Dachshunds
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| − | *Bilateral axillary hyperpigmentation, [[Skin Glossary - Pathology|lichenification, alopecia]]
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| − | *May be followed by [[Bacterial skin infections - Pathology#Pyoderma|secondary pyoderma]] or [[Skin Other - Pathology#Secondary seborrhea|seborrhea]]
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| − | *Microscopically:
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| − | **Thickened epidermis by mainly [[Skin Glossary - Pathology|acanthosis]]
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| − | **[[Skin Glossary - Pathology|Hyperkeratosis]]
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| − | **Increased melanin in epidermis
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| − | ondary
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| − | [[Category:Integumetary System - Developmental Pathology]]
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| − | ===Alopecia and Hypotrichosis===
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| − | *Occurs in most species
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| − | *Bred for in some breeds, e.g. Mexican hairless dog, Sphinx cat
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| − | *May be due to decreased number of hair follicles, failure of hair growth or follicular dysplasia
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| − | *Also associated with maternal deficiency of iodine
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| − | [[Category:Integumetary System - Developmental Pathology]]
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| − | ===Collagen Dysplasia===
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| − | [[Image: Collagen dysplasia.jpg|100px|thumb|right|<small><center>Collagen dysplasia - dog tail (Courtesy of Bristol BioMed Image Archive)</center></small>]]
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| − | *Occurs in many species
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| − | *Very stretchy and loose skin that tears easily
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| − | *Due to variety of defects of enzyme necessary for collagen synthesis or processing
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| − | *Histologically:
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| − | **Varies depending on cause
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| − | **May appear normal
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| − | **Collagen bundles varied in shape, size and their organisation
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| − | [[Category:Integumetary System - Developmental Pathology]]
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| − | ===Epidermolysis Bullosa===
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| − | [[Image: Epidermolysis bullosa.jpg|100px|thumb|right|<small><center>Epidermolysis bullosa in a lamb (Courtesy of Bristol BioMed Image Archive)</center></small>]]
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| − | *Also called '''Red Foot Disease'''
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| − | *Occurs in sheep, dogs, cattle and horses
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| − | *Development of cutaneous blisters
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| − | *Varies depending on hereditary cause
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| − | *Affected animals tend not to survive
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| − | *Lesions appear at surfaces that are easily damaged, ''e.g.'' oral mucosa, feet
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| − | *Microscopically:
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| − | **Epidermal vesicular disease
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| − | **Healing displaces lesions more dorsally
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| − | **May become infected and form [[Skin Glossary - Pathology|pustules]]
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| − | [[Category:Integumetary System - Developmental Pathology]]
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| − | ===[[Epitheliogenesis Imperfecta]]===
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| − | ===Hypertrichosis===
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| − | *Increased hair growth
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| − | *Both congenital or hereditary
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| − | *In sheep may be caused by [[Flaviviridae#Pestiviruses|Border Disease virus]]
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| − | *Microscopically:
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| − | **Enlarged primary follicles and wool fibres
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| − | *Also accociated with maternal hyperthermia
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| − | ===Ichthyosis===
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| − | *Inherited cutaneous disease
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| − | *Occurs in dogs and cattle
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| − | *Grossly:
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| − | **Thickened skin due to [[Skin Glossary - Pathology|hyperkeratosis]]
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| − | **May crack resembling fish scales
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| − | *Increased adherence of keratocytes preventing normal desquamation
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| − | *In cattle occurs in two forms:
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| − | **Ichthiosis fetalis - fatal, stillborn calves or die within days of birth
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| − | **Ichthiosis congenita - folded and thickened skin, fissures and partial [[Skin Glossary - Pathology|alopecia]]
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| − | [[Category:Integumetary System - Developmental Pathology]]
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| − | ===Photosensitisation===
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| − | *May be due to inherited defects
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| − | *See [[Skin Environmental - Pathology#Photosensitisation|HERE]]
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| − | ===Porcine Juvenile Pustular Psoriasiform Dermatitis===
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| − | *Also called '''Pityriasis Rosea'''
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| − | *Occurs in pigs
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| − | *Symmetric lesions on the abdomen, loin and medial thigh
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| − | *Start as small [[Skin Glossary - Pathology|papules]] covered by brown [[Skin Glossary - Pathology|crusts]]
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| − | *-> lesions join and spread -> umbilicated [[Skin Glossary - Pathology|plaques]] containing white centres with erythematous and scaly borders
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| − | *Similar to [[Skin Infectious - Pathology|dermatophytosis]]
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| − | *Histologically:
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| − | **Epidermal hyperplasia, [[Skin Glossary - Pathology|parakeratosis]], epidermal [[Skin Glossary - Pathology|pustules]] and superficial perivascular dermatitis
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| − | *For more detail see [[Porcine Juvenile Pustular Psoriasiform Dermatitis]]
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| − | [[Category:Integumetary System - Developmental Pathology]]
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| − | ===Zinc-related disorders===
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| − | *Occurs in Bullterriers and calves
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| − | *Resolves with zinc supplementation in calves but not dogs
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| − | *In dogs:
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| − | **Fatal acrodermatitis
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| − | **Lesions start between digits and on foot pads -> severe interdigital pyoderma -> [[Skin Glossary - Pathology|paronychia]] and [[Skin Glossary - Pathology|hyperkeratosis]] of pads
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| − | **May also occur on pinnae, elbows, muzzle, hocks or become generalised with [[Skin Glossary - Pathology|crusting, ulceration]] and secondary pyoderma
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| − | **Histologically:
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| − | ***Hyperkeratosis and bacterial pustular dermatitis
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| − | [[Category:Integumetary System - Developmental Pathology]]
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