Difference between revisions of "Bacterial skin infections - Pathology"

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#REDIRECT[[:Category:Integumentary System - Bacterial Infections]]
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{{toplink
 
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|backcolour = FFCCCC
 
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|linkpage =Integumentary System - Pathology
 
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|linktext =Integumentary System
 
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|maplink = Integumentary System (Content Map) - Pathology
 
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|pagetype =Pathology
 
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|sublink1 = Skin Infectious - Pathology
 
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|subtext1 = SKIN INFECTIOUS
 
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Cutaneous bacterial infections tend to be called '''pyodermas'''. They are superficial, deep and are common in dogs, but less common in other species.
 
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===Superficial pyoderma===
 
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[[Image: Superficial pyoderma dog.jpg|100px|thumb|right|<small><center>Superficial pyoderma in a dog (Courtesy of Bristol BioMed Image Archive)</center></small>]]
 
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*Affects epidermis and upper infundibulum of hair follicles
 
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*No scarring when healed
 
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*Grossly:
 
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**Erythema
 
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**Alopecia
 
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**[[Skin Glossary - Pathology|Papules and pustules]]
 
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**[[Skin Glossary - Pathology|Crusts]]
 
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**[[Skin Glossary - Pathology|Epidermal collarettes]]
 
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*Microscopically:
 
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**Intraepidermal pustular dermatitis
 
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**Superficial suppurative folliculitis
 
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**Bacteria commonly not seen
 
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===[[Impetigo]]===
 
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====[[Dermatophilosis]]====
 
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====[[Greasy pig disease]]====
 
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====Ovine fleece rot====
 
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*Caused by [[:Category:Pseudomonas and Burkholderia species|''Pseudomonas'']] and excessive moisture
 
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*Prediscposes to [[Parasitic skin infections - Pathology#Myiasis|myiasis]]
 
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====Equine pastern folliculitis====
 
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* = '''Greasy heel'''
 
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*Secondary pyoderma
 
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*Affects caudal pastern and fetlock
 
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===Deep pyoderma===
 
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*Less common than superficial pyoderma
 
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*Occurs mainly in dogs
 
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*Affects infundibulum, isthmic portion of hair follicles and surrounding dermis and subcutis
 
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*Heals with scarring
 
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*Local lymph nodes are often affected
 
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*Often secondary to immunosuppression, follicular hyperkeratosis or [[Parasitic skin infections - Pathology#Demodicosis|demodicosis]]
 
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*May also be a sequele to [[Bacterial skin infections - Pathology#Superficial pyoderma|superficial pyoderma]]
 
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*Grossly:
 
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**[[Skin Glossary - Pathology|Crusted papules, pustules, alopecia, abscesses, nodules, fistulas, ulcers, haemorrhagic bullae]]
 
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**In dogs may look similar to [[Skin Environmental - Pathology#Pyotraumatic dermatitis|pyotraumatic dermatitis]]
 
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*Microscopically:
 
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**Pyogranulomatous folliculitis and furunculosis
 
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**Nodular or diffuse dermatitis
 
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**Panniculitis
 
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*May involve a foreign bodey reaction to follicular contents and draining sinuses develop
 
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*If chronic, scarring and loss of adnexa
 
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*Bacteria often isolated include [[:Category:Staphylococcus species|''Staphylococcus'' spp.]], especially ''S. intermedius'' in dogs, [[:Category:Streptococcus species|''Streptococcus'' spp.]], ''[[Corynebacterium pseudotuberculosis]]'', [[:Category:Pseudomonas and Burkholderia species|''Pseudomonas'']], [[:Category:Pasteurella and Mannheimia species|''Pasteurella'']], [[Proteus|''Proteus'']], [[Escherichia coli|''E.coli'']]
 
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====Staphylococcal folliculitis and furunculosis====
 
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*Occurs in dogs, horses, sheep and goats
 
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*Dogs:
 
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**Localised or generalised lesions
 
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**Affected areas include: muzzle, chin, bridge of nose, pressure points and interdigital areas
 
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**'''German Shepherd deep pyoderma'''
 
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***Genetically predisposed
 
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***Dorsal lumosacral, ventral adbomen  and thigh areas
 
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*Horses:
 
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**Areas under tack ususlly involved
 
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*Goats:
 
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**Extremities, ventral abdomen, udder, medial thigh, perineum tend to be affected
 
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*Sheep:
 
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**Adults: face, limbs and teats
 
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**Lambs: [[Lips - Anatomy & Physiology|lips]] and perineum
 
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====Subcutaneous abscesses====
 
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*Purulent exudate within dermis and subcutis
 
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*Commonly occurs in cats due to contamination of penetrating wounds
 
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*Surrounding wall of collagen and fibroblasts may develop
 
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*Common bacteria (often normal mouth flora)
 
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**[[Pasteurella multocida|''Pasteurella multocida'']], [[Fusobacterium|''Fusobacterium'' spp.]], [[:Category:Streptococcus species|beta - haemolytic streptococci]], [[Bacteroides|''Bacteroides'']]
 
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====Bacterial granulomatous dermatitis====
 
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*Usually due to saprophytes
 
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*Grossly:
 
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**Diffuse or nodular lesions
 
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**May ulcerate and form drainage fistulas
 
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*Microscopically:
 
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**Macrophages +/- multinucleated giant cells
 
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**[[Necrosis - Pathology#Caseation Necrosis|Caseous necrosis]] and [[Neutrophils|neutrophils]]
 
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*'''Mycobacterial granulomatous or pyogranulomatous lesions'''
 
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**Usually caused by ''[[Mycobacterium lepraemurium]]'' (feline leprosy) or other ''Mycobacteria''
 
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**Most commonly lesions appear on head, neck and legs
 
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*'''Botryomycosis'''
 
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**Granulomatous dermatitis caused by nonfilamentous bacteria
 
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**Usually [[:Category:Staphylococcus species|''Staphylococcus aureus'']]
 
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**Small, yellow granules are formed - sulfur granules
 
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***Central bacteria surrounded by homogeneous eosinophilic material
 
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*Filamentous bacteria can also cause granulomas
 
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**''E.g.'' [[:Category:Actinomycetes|''Actinomyces'' and ''Nocardia'']], [[:Category:Actinobacillus species|''Actinobacillus'']]
 
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===Bacterial pododermatitis===
 
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*Digital infections in ruminants
 
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*'''Contagious footrot'''
 
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**Usually caused by [[Bacteroides|''Bacteroides nodosus'']] together with [[Fusobacterium|''Fusobacterium necrophorum'']]
 
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**Moisture and trauma allow ''B. nodosus'' to enter -> aids bacterial penetration of epidermis -> ''F. necrophorum'' invades -> necrosis and inflammation
 
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**Grossly:
 
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***Early lesions - red, moist, swollen, eroded interdigital skin
 
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***Spreads to epidermal matrix of hoof -> separation of horn + malodorous exudate
 
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***Regeneration attempted as germinal epithelium is not destroyed
 
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***Chronic infections -> long , misshapen hoof
 
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**Benign footrot (scald)- only interdigital ski affected, slight separation of heel horn
 
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***Mostly the type occuring in cattle
 
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*'''Necrobacillosis''' of the foot
 
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**Usually caused by [[Fusobacterium|''Fusobacterium necrophorum'']] with other bacteria
 
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**In sheep:
 
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***'''Ovine interdigital dermatitis'''
 
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****Acute necrotising dermatitis similar to benign footrot
 
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***'''Foot abscesses'''
 
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****Bulbular or lamellar
 
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****Mostly in wet conditions and in heavy sheep
 
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**In cattle:
 
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***'''Interdigital dermatitis and cellulitis'''
 
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***Caused by ''F. necrophorum'' and [[Bacteroides|''Bacteroides melaninogenicus'']]
 
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***Predisposed by trauma
 
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***Grossly:
 
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****Fissures, necrotic swollen edges in interdigital spaces
 
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****Inflammation may spread to joint spaces
 
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===Systemic bacterial infections===
 
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*[[Salmonella|'''Salmonellosis''']]
 
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**Capillary dilatation and congestion -> cyanosis of external ears and abdoman
 
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**Thrombosis -> necrosis of extremities
 
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*'''Erysipelas''' in pigs
 
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**Caused by [[Erysipelothrix rhusiopathiae|''Erysipelothrix rhusiopathiae'']]
 
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**Vasculitis, thrombosis, ischaemia -> cutaneous lesions - firm, raises, rhomboidal pink to dark purple areas
 
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*[[Clostridium novyi|''Clostridium novyi'']]
 
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**Severe cellulitis, toxaemia and death of young rams during breeding season (due to traumatised heads) - 'big head'
 
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*[[Streptococcus equi subsp. equi|''Streptococcus equi'']]
 
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**In horses
 
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**Immune complex vasculitis -> [[Haemorrhage - Pathology#Purpura haemorrhagica|purpura]]
 

Latest revision as of 19:12, 21 February 2011