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{{review}}
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{{toplink
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|backcolour = FFCCCC
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|linkpage =Integumentary System - Pathology
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|linktext =Integumentary System
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|maplink = Integumentary System (Content Map) - Pathology
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|pagetype =Pathology
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}}
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===General===
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#REDIRECT[[:Category:Integumentary System - Nutritional Pathology]]
*Often combined deficiency which improves when animal is fed a balnced diet
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*Sometimes caused by change in demand (pregnancy, growth, cold weather) or due to disease
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===Zinc deficiency===
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*Mainly in dogs and pigs, sometimes ruminants
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*'''In pigs''':
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**Grossly:circumscribed reddened papules and plaques, thick crusting and scaling, fissures along ventral abdomen and medial thighs, sometimes generalised
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**Microscopically: parakeratosis, acantosis, pseudoepitheliomatous hyperplasia, hypergranulosis
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**Commonly secondary bacterial dermatitis
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*'''In dogs''':
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**Siberian huskies and Alaskan malamutes:
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***Grossly: scales and crusts around mouthm chin, eyes, joints, prepuse, scrotum, vulva
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***Microscopically: diffuse hyperkeratosis extending to follicles, superficial perivascular dermatitis with eosinophils
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**Rapidly growing puppies:
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***Grossly: scaly plaques on skin, nasal planum and foot pads
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*'''In ruminants''':
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**Grossly: alopecia, crusts and scales on face, neck and distal extremities and mucocutaneous junctions
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**Microscopically: parakeratosis, sometimes hyperkeratosis
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===Copper deficiency===
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*Hair or wool depigmentation
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**Black sheep develop bands of lighter colouring
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**Cattle develop spectacle pattern of depigmentation around eyes)
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**Coat colour may change from black to reddish brown
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===Vitamin A deficiency===
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*In dogs
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*Grossly: generalised scaling
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*Microscopically: marked follicular hyperkeratosis
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===Vitamin E deficiency===
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*Steatitis may develop in cats fed excess fatty acids or with vitamin E deficincy
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*Grossly: firm, yellow or orange nodules in subcutaneous tissue
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*Microscopically: nodular to diffuse granulomatous panniculitis, macrophages and giant cells, oedema, fat necrosis, neutrophils and ceroid pigment
 
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