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Created page with "(DJD) right|thumb|100px|<small><center>DJD in a horse (Image sourced from Bristol Biomed Image Archive with permission)</center></small> *'''Osteoarthriti..."
(DJD)
[[Image:DJD horse.jpg|right|thumb|100px|<small><center>DJD in a horse (Image sourced from Bristol Biomed Image Archive with permission)</center></small>]]
*'''Osteoarthritis, osteoarthrosis'''
*Due to acceleration of normal ageing process - wear and tear
*Destructive disease leading to:
**Loss of weight-bearing [[Joints - Anatomy & Physiology#Articular cartilage|articular cartilage]]
**Erosion, fibrillation of cartilage
***Clefts in the cartilage, perpendicular to the surface
**Complete exposure of underlying bone
***Bone appears polishes, dense - [[Musculoskeletal Terminology - Pathology|eburnation]]
***Radiographically - joint space reduction due to loss of cartilage
**[[Musculoskeletal Terminology - Pathology|Osteophyte]] formation at joint margins
**Remodelling of adjacent bone
**Brown/yellow discolouration
**Synovial hypertrophy
**Capsular fibrosis
*May affect one or multiple joints
*May or may not be symptomatic
*Pathogenesis:
**Not entirely clear but linked to loss of [[Joints - Anatomy & Physiology#Articular cartilage|proteoglycans]] and subsequent lubrication
**Increased water content due to improper binding -> softening of cartilage = chondromalacia
*Predisposing factors:
**Persistent trauma
**Joint instability / dysplasia
***[[Joints Degenerative - Pathology#Luxations and subluxations|Luxations and subluxations]]
***[[Hip Dysplasia|Hip dysplasia]]
***[[Elbow Dysplasia|Elbow dysplasia]]
**Conformational abnormalities / congenital malformations
**[[Osteochondrosis|Osteochondrosis dissecans]]
**Intra-articular fractures
**[[Joints Degenerative - Pathology#Calve Legg-Perthe's disease|Calve Legg-Perthe's disease]]
[[Category:Joints - Degenerative Pathology]]
[[Image:DJD horse.jpg|right|thumb|100px|<small><center>DJD in a horse (Image sourced from Bristol Biomed Image Archive with permission)</center></small>]]
*'''Osteoarthritis, osteoarthrosis'''
*Due to acceleration of normal ageing process - wear and tear
*Destructive disease leading to:
**Loss of weight-bearing [[Joints - Anatomy & Physiology#Articular cartilage|articular cartilage]]
**Erosion, fibrillation of cartilage
***Clefts in the cartilage, perpendicular to the surface
**Complete exposure of underlying bone
***Bone appears polishes, dense - [[Musculoskeletal Terminology - Pathology|eburnation]]
***Radiographically - joint space reduction due to loss of cartilage
**[[Musculoskeletal Terminology - Pathology|Osteophyte]] formation at joint margins
**Remodelling of adjacent bone
**Brown/yellow discolouration
**Synovial hypertrophy
**Capsular fibrosis
*May affect one or multiple joints
*May or may not be symptomatic
*Pathogenesis:
**Not entirely clear but linked to loss of [[Joints - Anatomy & Physiology#Articular cartilage|proteoglycans]] and subsequent lubrication
**Increased water content due to improper binding -> softening of cartilage = chondromalacia
*Predisposing factors:
**Persistent trauma
**Joint instability / dysplasia
***[[Joints Degenerative - Pathology#Luxations and subluxations|Luxations and subluxations]]
***[[Hip Dysplasia|Hip dysplasia]]
***[[Elbow Dysplasia|Elbow dysplasia]]
**Conformational abnormalities / congenital malformations
**[[Osteochondrosis|Osteochondrosis dissecans]]
**Intra-articular fractures
**[[Joints Degenerative - Pathology#Calve Legg-Perthe's disease|Calve Legg-Perthe's disease]]
[[Category:Joints - Degenerative Pathology]]