Difference between revisions of "Category:Streptococcus species"

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(Created page with '{{review}} ===Overview=== *Cause suppurative infections in many different animals *Cause abscess formation and septicaemia *Cause mastitis, metritis, polyarthritis, meningitis …')
 
 
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===Overview===
 
===Overview===
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*Haemolytic streptococci of Lancefield group C are common inhabitants of the equine nasopharynx  
 
*Haemolytic streptococci of Lancefield group C are common inhabitants of the equine nasopharynx  
 
*''Streptococcus zooepidemicus'' and ''S. equisimilis'' are usually non-pathogenic
 
*''Streptococcus zooepidemicus'' and ''S. equisimilis'' are usually non-pathogenic
*Involved in [[Peritoneal Cavity Inflammatory - Pathology#In pigs|peritonitis in pigs]],  [[Pleural Cavity & Membranes Inflammatory - Pathology#Pyothorax (Thoracic empyema)|pyothorax]], [[Bones Inflammatory - Pathology#Osteomyelitis|osteomyelitis]], [[Cavity & Gingiva - Pathology#Catarrhal Stomatitis|catarrhal stomatitis]]
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*Involved in [[Peritonitis#In pigs|peritonitis in pigs]],  [[Pyothorax|pyothorax]], [[Osteomyelitis|osteomyelitis]], [[Stomatitis|catarrhal stomatitis]]
*In infectious [[Joints Inflammatory - Pathology#In Sheep|arthritis of sheep]], [[Joints Inflammatory - Pathology#In Cattle|arthritis in calves]], [[Joints Inflammatory - Pathology#In Horses|arthritis in horses]] and [[Joints Inflammatory - Pathology#In Pigs|arthritis in pigs]]
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*In infectious [[Infectious Arthritis#In Sheep|arthritis of sheep]], [[Infectious Arthritis#In Cattle|arthritis in calves]], [[Infectious Arthritis#In Horses|arthritis in horses]] and [[Infectious Arthritis#In Pigs|arthritis in pigs]]
 
*Often commensals on mucous membranes of upper respiratory and lower urogenital tract
 
*Often commensals on mucous membranes of upper respiratory and lower urogenital tract
 
*Opportunistic infections
 
*Opportunistic infections
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===Pathogensis and Pathogenicity===
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===Pathogenesis and Pathogenicity===
  
 
*Beta-haemolytic strains more pathogenic than alpha-haemolytic strains
 
*Beta-haemolytic strains more pathogenic than alpha-haemolytic strains
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'''in sheep'''
  
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*[[:Category:Streptococcus species|'''''Streptococcus'' spp.''']]
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**Commonly cause suppurative polyarthritis in lambs
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**Naval infection -> bacteriamia -> polyarthritis
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***May also cause blindness and nervous signs if uvea or meninges are affected
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**Larger joints are more afected
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***May spread to other organs
  
===[[Respiratory Bacterial Infections - Pathology#Strangles|Strangles]]===
 
  
*Epidemiology
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'''in cattle'''
**[[Respiratory Bacterial Infections - Pathology#Strangles|Strangles]] is a highly infectious disease of horses caused by ''Streptococcus equi'' subsp. ''equi''
 
**[[Respiratory Bacterial Infections - Pathology#In Horses|upper respiratory tract disease of horses]] with fever and abscessation of regional lymph nodes
 
**Causes [[Nasal Cavity Inflammatory - Pathology#Strangles|rhinitis]], [[Nasopharynx Inflammatory - Pathology|pharyngitis]], lymphadenitis and [[Muscles Inflammatory - Pathology#Abscesses|myositis]]
 
**Outbreaks in groups of young horses
 
**Transmitted via purulent exudate discharging from upper respiratory tract or from lymph nodes
 
**Chronic, carrier state can occur with bacteria im the guttural pouch
 
**A mild, atypical form can occur
 
**''S. equi'' shed for 4 weeks beyond clinical resolution
 
  
*Clinical signs
 
**Incubation period 3 to 6 days
 
**Fever, depression, anorexia
 
**Purulent nasal discharge
 
**Swollen, painful regional lymph nodes, especially submandibular
 
**Abscessation and rupture of lymph nodes
 
**Guttural pouch empyema
 
**100% morbidity; 5% mortality
 
**Death can occur from pneumonia, breathing difficulties from swollen lymph nodes or [[Muscles Degenerative - Pathology#Ischaemia|purpura haemorrhagica]](an immune-mediated disease)
 
**Bastard strangle may occasionally occur, with abscessaation in many organs of the body
 
**''S. equi'' may be involved in [[Bacterial skin infections - Pathology#Systemic bacterial infections|cutaneous lesions]]
 
  
*Diagnosis
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*Neonatal polyarthritis by:
**Clinical signs and history
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***Via umbilicus
**Mucoid colonies with beta-haemolysis
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***Also involves eyes and meninges
**Sugar fermentation allows differentiation of ''S. equi'' from ''S. zooepidemicus'' and ''S. equisimilis''
 
**PCR to detect asymptomatic carriers
 
  
*Treatment and control
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[[Category:Bacterial Organisms]]
**Penicillin administration to in-contact animals
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[[Category:Gram_positive_bacteria]]
**Isolation of affected animals
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[[Category:Cocci]]
**Quarantne in-coming animals
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[[Category:To_Do_-_Bacteria]]
**Avoid overcrowding and mixing different age groups
 
**Disinfection of equipment
 
 
 
===''Streptococcus suis''===
 
 
 
*Meningitis, arthritis, septicaemia and [[Respiratory Bacterial Infections - Pathology#Streptococcal pneumonia|pneumonia]] of pigs
 
*Sporadic cases of endocarditis, neonatal deaths and abortion
 
*Carried in tonsils and nasal cavity of carrier pigs
 
*Outbreaks occur in intensively-reared herds with poor hygiene
 
*Carrier sows infect litters causing neonatal deaths
 
*Meningitis with fever, tremors, incoordination, opisthotonos and convulsions
 
*Treatment with penicillin; prophylactic long-acting penicillin for sows and piglets
 
*Suppurative conditions in cattle, sheep, horses, cats
 
*Septicaemia and meningitis in humans
 
 
 
 
 
===Bovine streptococcal mastitis===
 
 
 
*''S. agalactiae, S. dysgalactiae'' and ''S. uberis'' primarily cause mastitis
 
*Also ''S. pyogenes, S. zooepidemicus'' and ''Enterococcus faecalis'' can be involved
 
*''S. agalactiae'' colonises milk ducts causing persistent infections with acute outbreaks
 
*''S. dysgalactiae'' found in the oral cavity and on the skin of the udder causes acute mastitis
 
*''S. uberis'' inhabits normal skin, tonsils and vaginal mucosa, and causes mastitis without systemic signs
 
*Cause inflammation of mammary tissue and clots form in milk
 
*Milk samples are cultured on blood agar, Edward's medium and MacConkey agar for diagnosis
 
 
 
 
 
===''S. equisimilis''===
 
 
 
*Found on skin and vagina of horses
 
*Causes abscesses, endometritis and mastitis in horses
 
*Suppurative conditions in pigs, cattle, dogs, birds
 
 
 
 
 
===''S. zooepidemicus''===
 
 
 
*Colonises mucous membranes
 
*Causes mastitis, pneumonia, [[Paranasal Sinuses Inflammatory - Pathology|sinusitis]] and navel infections in horses
 
*''S. zooepidemicus'' can cause similar signs to [[Respiratory Bacterial Infections - Pathology#Strangles|strangles in horses]] and may accompany [[Bronchi and Bronchioles Inflammatory - Pathology#Chronic obstructive pulmonary disease (COPD)|COPD]]
 
*Secondary invador after [[Respiratory Viral Infections - Pathology#Equine influenza|equine influenza]]
 
*Colonises skin and mucous membranes of cattle, lambs, pigs and poultry and causes suppurative infections and septicaemia
 
* Can cause vascular fragility, leading to [[Haemostasis - Pathology#Haemorrhagic Disease Due To Vascular Fragility|haemorrhagic disease]]
 
 
 
 
 
===''Enterococcus faecalis''===
 
 
 
*Colonises intestinal tract
 
*Causes opportunistic suppurative infections in many species
 
 
 
 
 
===''S. canis''===
 
 
 
*Found in vagina and anal mucosa of carnivores
 
*Neonatal septicaemia, suppurative infections, toxic shock syndrome
 
*In [[Bacterial skin infections - Pathology#Deep pyoderma|deep pyoderma]] and subcutaneous abscesses
 
 
 
 
 
===''S. pneumoniae''===
 
 
 
*Found in upper respiratory tract of primates
 
*Causes septicaemia, pneumonia and meningitis
 
*Pneumonia in guinea-pigs and rats
 
 
 
 
 
===''S. porcinus''===
 
 
 
*Submandibular lymphadenitis in pigs
 
[[Category:Bacteria]][[Category:Gram_positive_bacteria]][[Category:Cocci]]
 

Latest revision as of 16:33, 3 March 2011


Overview

  • Cause suppurative infections in many different animals
  • Cause abscess formation and septicaemia
  • Cause mastitis, metritis, polyarthritis, meningitis
  • Primary or secondary infections following viral infection
  • Neonatal septicaemia related to maternal genital tract infection
  • Haemolytic streptococci of Lancefield group C are common inhabitants of the equine nasopharynx
  • Streptococcus zooepidemicus and S. equisimilis are usually non-pathogenic
  • Involved in peritonitis in pigs, pyothorax, osteomyelitis, catarrhal stomatitis
  • In infectious arthritis of sheep, arthritis in calves, arthritis in horses and arthritis in pigs
  • Often commensals on mucous membranes of upper respiratory and lower urogenital tract
  • Opportunistic infections


Characteristics

  • Gram positive cocci forming chains
  • Catalase negative, facultative anaerobes
  • Fastitidious - require enriched media such as blood or serum
  • Small haemolytic, translucent colonies, some mucoid
  • Catalase negative
  • Susceptible to desiccation


Identification

  • Beta haemolysis (complete with clear zones surrounding colonies)
  • Alpha haemolysis (partial with green zones surrounding colonies)
  • Lancefield grouping - serology based on group-specific polysaccharide in cell wall
  • Biochemical testing


Diagnosis

  • Swabs of pus or exudate cultured on blood agar and MacConkey agar
  • No growth on MacConkey except S. faecalis
  • PCR, Lancefield grouping and biochemical tests


Pathogenesis and Pathogenicity

  • Beta-haemolytic strains more pathogenic than alpha-haemolytic strains
  • Virulence factors include streptolysins, hyaluronidase, DNase, streptokinase and proteases
  • S. pyogenes, S. pneumoniae and some strains of S. equi have polysaccharide capsules which are antiphagocytic
  • S. pyogenes and S. equi have antiphagocytic cell wall M proteins


in sheep

  • Streptococcus spp.
    • Commonly cause suppurative polyarthritis in lambs
    • Naval infection -> bacteriamia -> polyarthritis
      • May also cause blindness and nervous signs if uvea or meninges are affected
    • Larger joints are more afected
      • May spread to other organs


in cattle


  • Neonatal polyarthritis by:
      • Via umbilicus
      • Also involves eyes and meninges