Difference between revisions of "Muscles Developmental - Pathology"

From WikiVet English
Jump to navigation Jump to search
 
(4 intermediate revisions by the same user not shown)
Line 1: Line 1:
===[[Myofibrillar Hypoplasia]]===
+
#REDIRECT[[:Category:Muscles - Developmental Pathology]]
 
 
 
 
 
 
 
 
===[[Muscle Fibre Hyperplasia]]==
 
 
 
 
 
 
 
 
 
===[[Muscular Dystrophy]]===
 
 
 
 
 
 
 
 
 
===Glycogen storage diseases===
 
 
 
*Caused by a deficiency of an enzyme
 
*See [[Glycogen Infiltration|general pathology]]
 
*Type II glycogenosis
 
**Deficiency of acid maltase
 
**In Shorthorn cattle
 
**Muscular weakness and incoordination
 
**Glycogen stored in skeletal muscle, heart and CNS
 
**Type I and II muscle fibres contain glycogen vacuoles
 
*Type III glycogenosis
 
**Deficiency of debranching enzyme
 
**In dogs
 
**Causes [[Hypertrophic Cardiomyopathy|hypertrophic cardiomyopathy]] and hepatomegaly
 
**Glycogen in skeletal and cardiac muscle, neurons nad hepatocytes
 
 
 
[[Category:Muscles - Developmental Pathology]]
 
 
 
 
 
===Steatosis===
 
 
 
*Also called '''lipomatosis'''
 
*In cattle, sheep and pigs
 
*Fat replaces lost muscle fibres
 
*Pale muscle, bilaterally symmetrical
 
*No clinical significance
 
*Noticed at slaughter or necropsy
 
 
 
[[Category:Muscles - Developmental Pathology]]
 
 
 
 
 
===Myasthenia gravis (MG)===
 
 
 
*'''Acquired'''
 
**Autoimmune disease
 
***Antibodies directed against acetyl choline receptors
 
**Associated with [[Thymus neoplasia|thymomas]], [[Megaoesophagus|megaoesophagus]] and dysphagia
 
**In adult dogs
 
*'''Congenital'''
 
**Inherited deficiency in acetyl choline receptors
 
**Rare
 
**Newfoundland, Jack Russel Terrier, Springer Spaniels – genetic predisposition
 
**In dogs – 4 DLA genes recognized: DLA-12, DLA-88, DLA-79 and DLA-64
 
**Associated with HLA gene in humans
 
**No antibodies against acetyl choline receptors in serum
 
**Non-specific muscle [[Muscles Degenerative - Pathology#Atrophy|disuse atrophy]] and fibrosis or no changes on histology
 
*Both forms manifest as weakness which worsens on exercise
 
 
 
[[Category:Muscles - Developmental Pathology]]
 
 
 
 
 
===[[Canine Dermatomyositis]]===
 
 
 
===[[Muscles Degenerative - Pathology#Porcine stress syndrome|Porcine stress syndrome]]===
 
 
 
 
 
[[Category:Musculoskeletal System - Pathology]]
 

Latest revision as of 17:39, 3 March 2011