Changes

*Firstly [[Muscles Degenerative - Pathology#Necrosis|segmental necrosis]]  

*Firstly [[Muscle Necrosis|segmental necrosis]]  

*-> death of satellite cells  

*-> death of satellite cells  

**Causes [[Muscle Regeneration|regeneration]] but myoblast precursors have to be recruited from viable fibres

**Causes [[Muscle Regeneration|regeneration]] but myoblast precursors have to be recruited from viable fibres

**Infarction from embolism is rare due to collateral circulation

**Infarction from embolism is rare due to collateral circulation

**Extension of infarcts depends on size of vessels occluded

**Extension of infarcts depends on size of vessels occluded

***Small capillaries -> segmental [[Muscles Degenerative - Pathology#Necrosis|necrosis]]

***Small capillaries -> segmental [[Muscle Necrosis|necrosis]]

***Large arteries -> whole muscle areas, including sattelite cells, are killed

***Large arteries -> whole muscle areas, including sattelite cells, are killed

**Healed by fibrosis

**Healed by fibrosis