Difference between revisions of "Neospora"
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**In cattle, vertical transmission occurs | **In cattle, vertical transmission occurs | ||
***Post-natal infection occurs but is less common | ***Post-natal infection occurs but is less common | ||
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| + | *''Neospora caninum'' in [[Parasitic Myositis#Protozoa|myositis]] | ||
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'''Pathogenesis''' | '''Pathogenesis''' | ||
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<big> | <big> | ||
'''[[Neosporosis - Dog|Dog Neosporosis]] | '''[[Neosporosis - Dog|Dog Neosporosis]] | ||
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| + | '''[[Neosporosis - Cattle|Cattle Neosporosis]] | ||
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| + | '''[[Neosporosis - Horse|Horse Neosporosis]] | ||
| + | </big> | ||
| − | * | + | *''N. caninum'' |
| − | ** | + | **Necrotising inflammation of muscles |
| − | ** | + | **Myositis more severe than in toxoplasmosis |
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| − | + | ''N. caninum'' - A disease of cattle with late abortion of mummified or autolysed foetus. May also get foetal malformation, e.g. arthrogryposis. | |
| − | + | ==Test yourself with the Tissue Cyst Forming Coccidian Flashcards== | |
| − | + | [[Tissue_Cyst_Forming_Coccidian_Flashcards|Tissue Cyst Forming Coccidian Flashcards]] | |
| − | + | [[Category:Tissue Cyst Forming Coccidia]] | |
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| − | + | [[Category:To_Do_-_Parasites]] | |
Latest revision as of 23:01, 5 March 2011
- 2 main species
- Neospora caninum in the dog
- Neospora hughesi in the horse
- Sporulated oocysts measuring just 10μm
- Oocyst contains 2 sporocysts with 4 sporozoites
- Route of transmission not fully understood
- Often misdiagnosed as Toxoplasma gondii
- Sarcocystis cysts have thicker walls
- Infection diagnosed by IFAT, ELISA or PCR
- Identification of lesions and organisms in tissue using immunohistochemical staining
- Eliminate other causes of abortion first
Life cycle
- Life cycle similar to Toxoplasma gondii
- Limited range of warm-blooded intermediate hosts
- Asexual reproduction occurs in intermediate host forming tissue cysts
- Host range of sexual stage is unknown for N.caninum
- Intermediate host for N.hughesi is the horse, but the definitive host is unknown
- Final host
- Dogs pass oocysts
- Role not fully understood in pathogenesis
- 5 day prepatent period
- Other wild canids may also act as final definitive hosts
- Intermediate host
- Mostly cattle
- Natural infection has been documented in other herbivores
- Transmission
- Transplacental infection occurs in all intermediate hosts and in the canine final host
- Transplacental transmission can occur in successive pregnancies
- In cattle, vertical transmission occurs
- Post-natal infection occurs but is less common
- Transplacental infection occurs in all intermediate hosts and in the canine final host
- Neospora caninum in myositis
Pathogenesis
- N. caninum
- Necrotising inflammation of muscles
- Myositis more severe than in toxoplasmosis
N. caninum - A disease of cattle with late abortion of mummified or autolysed foetus. May also get foetal malformation, e.g. arthrogryposis.