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| − | {{review}}
| + | [[Central Nervous System Inflammation Overview]] |
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| − | {{toplink
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| − | |backcolour = E0EEEE
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| − | |linkpage = Nervous System - Pathology
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| − | |linktext =Nervous System
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| − | |maplink = Nervous System (Content Map) - Pathology
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| − | |pagetype =Pathology
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| − | }}
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| − | <br>
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| | ==Introduction== | | ==Introduction== |
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| | *** This is rare. | | *** This is rare. |
| | *** Usually associated with septicemia or infarcts. | | *** Usually associated with septicemia or infarcts. |
| | + | |
| | + | ==Clinical Signs of CNS Inflammation== |
| | + | |
| | + | * Signs often reflect multiple levels of neurological involvement. |
| | + | * Generalised [[Forebrain Disease - Pathology#Clinical Signs|forebrain signs]] are seen. |
| | + | * Neck pain may be seen alone, or with other signs. |
| | + | |
| | + | ==Diagnosis== |
| | + | |
| | + | * History, physical and neurological examination. |
| | + | * Fundic examination may give clues as to whether a systemic infection is present. |
| | + | * CSF examination may help define the problem. |
| | + | |
| | + | ==Treatment== |
| | + | |
| | + | * Treatment is directed at a specific cause, if one can be found. |
| | + | ** If a cause cannot be found, trimethoprim, clindamycin or doxycycline plus or minus corticosteroids may be used. |
| | + | |
| | + | [[Category:Central Nervous System - Inflammatory Pathology]] |
| | + | |
| | + | [[Central Nervous System Infectious Inflammation]] |
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| | ==Routes of Entry== | | ==Routes of Entry== |
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| | ==[[Prion Disease]]== | | ==[[Prion Disease]]== |
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| − | ==Non-Infectious Inflammatory Diseases==
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| − | ===Granulomatous Meningoencephalitis (GME)=== | + | [[Category:Central Nervous System - Inflammatory Pathology]] |
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| | + | |
| | + | ==[[:Category:CNS Non-Infectious Inflammatory Diseases]]== |
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| | + | ===[[Granulomatous Meningoencephalitis]]=== |
| | + | (GME) |
| | * An [[CNS Idiopathic Conditions - Pathology|idiopathic CNS conditon]] | | * An [[CNS Idiopathic Conditions - Pathology|idiopathic CNS conditon]] |
| | * May occur as: | | * May occur as: |
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| | ** This is only appropriate if there is a focal mass. | | ** This is only appropriate if there is a focal mass. |
| | * Radiation therapy. | | * Radiation therapy. |
| | + | |
| | + | [[Necrotising Meningoencephalitis]] |
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| | ===Pug Encephalitis=== | | ===Pug Encephalitis=== |
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| | * The disease is uniformly fatal. | | * The disease is uniformly fatal. |
| | ** Corticosterid treatment has no effect. | | ** Corticosterid treatment has no effect. |
| − |
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| − | ==Clinical Signs of CNS Inflammation==
| |
| − |
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| − | * Signs often reflect multiple levels of neurological involvement.
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| − | * Generalised [[Forebrain Disease - Pathology#Clinical Signs|forebrain signs]] are seen.
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| − | * Neck pain may be seen alone, or with other signs.
| |
| − |
| |
| − | ==Diagnosis==
| |
| − |
| |
| − | * History, physical and neurological examination.
| |
| − | * Fundic examination may give clues as to whether a systemic infection is present.
| |
| − | * CSF examination may help define the problem.
| |
| − |
| |
| − | ==Treatment==
| |
| − |
| |
| − | * Treatment is directed at a specific cause, if one can be found.
| |
| − | ** If a cause cannot be found, trimethoprim, clindamycin or doxycycline plus or minus corticosteroids may be used.
| |