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| − | [[Central Nervous System Inflammation Overview]] | + | #redirect[[:Category:Central Nervous System - Inflammatory Pathology]] |
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| − | [[Central Nervous System Infectious Inflammation]]
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| − | ==[[:Category:CNS Non-Infectious Inflammatory Diseases]]==
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| − | ===[[Granulomatous Meningoencephalitis]]===
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| − | (GME)
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| − | * An [[CNS Idiopathic Conditions - Pathology|idiopathic CNS conditon]]
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| − | * May occur as:
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| − | ** A disseminated disease
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| − | ** A focal mass lesion
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| − | ** A primary occular disease
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| − | * Brainstem signs are common, although the forebrain is primarily affected.
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| − | * May be incorrectly diagnosed as lymphoma.
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| − | * Changes are apparent in the CSF.
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| − | ** There is usually a mononucloear pleocytosis.
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| − | ** Sometimes only protein is elveated.
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| − | * Diffuse inflammatory changes or a mass lesion will be seen by advanced imaging.
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| − | ** However, biopsy is required for a definative diagnosis.
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| − | * Life span is between 6 months and 1 year from diagnosis.
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| − | ====Treatment====
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| − | * Immunosuppression:
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| − | ** Corticosteroids
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| − | ** Azathioprine
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| − | ** Cycophosphamide
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| − | * Surgery
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| − | ** This is only appropriate if there is a focal mass.
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| − | * Radiation therapy.
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| − | [[Necrotising Meningoencephalitis]]
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| − | [[:Category:CNS Non-Infectious Inflammatory Diseases]]
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| − | ===Pug Encephalitis===
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| − | * A [[CNS Idiopathic Conditions - Pathology|CNS idiopathic condition]]
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| − | * Affects pugs.
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| − | ** Similar conditions are seen in yorkshire and maltese terriers.
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| − | * Officially known as necrotising meningoencephalitis of small dogs.
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| − | * Characterised by histological forebrain inflammation and necrosis.
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| − | * The disease is uniformly fatal.
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| − | ** Corticosterid treatment has no effect.
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| − | [:Category:CNS Non-Infectious Inflammatory Diseases]]
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