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, 13:34, 8 March 2011
* A seizure is a brain disorder which manifests as paroxysmal cerebral dysrhythmia.
** The episode has a sudden onset and ceases spontaneously.
** Seizures tend to recur.
* In epilepsy, individuals appear to have a low seizure threshold.
** This predisposes their neurons to depolarize of their own volition.
* "Idiopathic epilepsy" is said to occur when no other cause of seizuring is apparent.
===Pathogenesis===
* All seizures arise from a small group of neurons that periodically and spontaneously depolarize.
* In addition to being idiopathic (i.e. low seizure threshold), this sudden, uncontrolled neuronal discharge can occur due to:
** Structural causes
*** Neoplasms
*** Inflammation
*** Trauma
** Biochemical causes
*** Hypocalcaemia
*** hypoglycaemia
*** Hepatic encephalopathy.
* Idiopathic epilepsy is a relatively common cause of generalised seizures in the dog.
** NOT in the cat.
* The onset of seizures is between 1 and 5 years of age.
* The condition presents as recurrent, unprovoked seizures, with no specific cause.
* There are no neurological defects between episodes.
* Seizures tend to start as generalised seizures, with no aura.
[[Category:Central Nervous System - Idiopathic Pathology]]