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| | ==[[Cognitive Dysfunction Syndrome]] == | | ==[[Cognitive Dysfunction Syndrome]] == |
| − | (CDS)
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| − | * CDS causes signs of senility.
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| − | * Increasing numbers of dogs and cats are suffering from CDS.
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| − | ** Prevalence is similar to that seen in humans: an 85 year-old human is roughly equivalent to a 15 year-old cat, and a 13-14 year-old dog.
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| − | *** Aging in dogs id breed specific.
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| − | ===Pathology===
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| − | * A number of changes are seen in the brains of geriatric animals which may cause the signs of CDS.
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| − | ** Vascular insufficiency leads to:
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| − | *** Hypoxia
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| − | *** Increased free redical production
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| − | *** Deposition of amyloid plaques
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| − | *** Modification of other brain proteins
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| − |
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| − | ===Treatment===
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| − | * There are no published studies related to treatment of CDS in animals.
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| − | * Potential therapies include:
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| − | ** Dietary modification
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| − | *** Diets are enriched with antioxidants, vitamin E, beta-carotene and essential fatty acids.
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| − | ** Environmental stimulation
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| − | ** Drugs
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| − | *** Selegiline
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| − | *** Propentofylline
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| − | *** Nicergoline
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| − | [[Category:Central Nervous System - Degenerative Pathology]]
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