Difference between revisions of "Contagious Bovine Pleuropneumonia"

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#redirect[[Mycoplasma mycoides subsp. mycoides]]
[[Image:Contagious bovine pleuropneumonia.jpg|right|thumb|100px|<small><center>Contagious bovine pleuropneumonia (Image sourced from Bristol Biomed Image Archive with permission)</center></small>]]
 
 
 
 
*Aerosol transmission by close contact with clinically or subclinically affected animals
 
*Severity depends on strain and host susceptibility
 
*Slow spread of infection
 
*50% morbidity; mortality rate high in severe outbreaks
 
*Large colony type causes pleuropneumonia, mastitis, septicaemia and polyarthritis
 
 
 
*Clinical signs
 
**Acute onset fever, anorexia, depression, lowered milk yield, hyperpnoea, coughing and a mucopurulent nasal discharge
 
**Dyspnoea occurs with abducted elbows and extended necks and an expiratory grunt
 
**Can be fatal within 1-3 weeks
 
**Calves may suffer from [[Joints Inflammatory - Pathology#In Cattle|arthritis]], synovitis and endocarditis
 
 
 
*Gross pathology
 
**Marbled appearance to lungs with consolidated grey and red lobules separated by emphysematous areas
 
**Serofibrinous pleural fluid
 
**Necrotic foci surrounded by fibrous capsules in chronic cases act as source of infection
 
 
 
*Diagnosis
 
**Clinical signs and post-mortem appearance
 
**PCR on pleural fluid, lung tissue, regional lymph nodes or bronchoalveolar lavage fluid
 
**Fluorescent antibody test
 
**Serological tests such as serum agglutination, haemagglutination, complement fixation, ELISA
 
 
 
*Treatment and control
 
**Slaughter of affected cattle in counries where the disease is exotic
 
**Movement restrictions, quaranteen and slaughter of carrier animals in endemic countries
 
*''M. mycoides'' subsp. 'mycoides'' causes septicaemia, pleuropneumonia, arthritis and mastitis in goats
 
**Vaccination in endemic regions
 
*Caused by [[Mycoplasma mycoides subsp. mycoides|''Mycoplasma mycoides'']], small colony variant
 
*Causes a fibrinonecrotic [[Pneumonia Overview#Infectious causes of pneumonia|pneumonia]] and [[Pleural Cavity & Membranes Inflammatory - Pathology|fibrinous pleuritis]]
 
*Also affects caudodorsal areas
 
*[[Bronchopneumonia|Bronchopneumonia]] -> [[Lobar Pneumonia|lobar pneumonia]] 
 
*Sequestra are common
 
*NB: similarity to pneumonic pasteurellosis but CBPP has more pronounced marbled effect
 
*Interstitial septa are markedly widened by fibrinous exudate and the necrotic areas may have a fibrous capsule
 
*Large colony variant will cause a similar disease in goats
 
 
 
 
 
[[Category:Respiratory Diseases - Cattle]][[Category:To_Do_-_Clinical]]
 
[[Category:Respiratory_Bacterial_Infections]]
 

Latest revision as of 18:05, 14 March 2011