Author, Donkey, Bureaucrats, Administrators
53,803
edits
Changes
Jump to navigation
Jump to search
Pancreas, Endocrine - Degenerative Pathology (view source)
Revision as of 19:20, 25 March 2011
, 19:20, 25 March 2011no edit summary
===Aetiology===
===Aetiology===
*Hypoplasia of [[Pancreas - Anatomy & Physiology#Endocrine|panceatic islets]] where [[Pancreas - Anatomy & Physiology|exocrine]] cells are functional
*Hypoplasia of [[Pancreas - Anatomy & Physiology#Endocrine|panceatic islets]] where [[Pancreas - Anatomy & Physiology|exocrine]] cells are functional
*Degeneration of the [[Pancreas - Anatomy & Physiology#Endocrine|islet]] cells occurs in [[Pancreatic Necrosis, Acute|acute pancreatic necrosis]] along with acinar tissue necrosis, atrophy occurs during [[Pancreatitis, Chronic Interstitial|chronic interstitial pancreatitis]]
*Degeneration of the [[Pancreas - Anatomy & Physiology#Endocrine|islet]] cells occurs in [[Pancreatic Necrosis, Acute|acute pancreatic necrosis]] along with acinar tissue necrosis, atrophy occurs during [[Pancreatitis|chronic interstitial pancreatitis]]
*Extensive neoplastic destruction may also contribute to [[Pancreas - Anatomy & Physiology#Endocrine|islet]] loss
*Extensive neoplastic destruction may also contribute to [[Pancreas - Anatomy & Physiology#Endocrine|islet]] loss
*Causes [[DM|Diabetes mellitus]] (DM)
*Causes [[DM|Diabetes mellitus]] (DM)
**'''Amyloidosis''' of the [[Pancreas - Anatomy & Physiology#Endocrine|islets]] is sometimes observed and may be restricted to just them
**'''Amyloidosis''' of the [[Pancreas - Anatomy & Physiology#Endocrine|islets]] is sometimes observed and may be restricted to just them
***May result in signs of [[DM|DM]] or have no symptoms
***May result in signs of [[DM|DM]] or have no symptoms
***[[Degenerations and Infiltrations - Pathology#Vacuolar Degeneration|Hydropic (vacuolar) degeneration]] of beta cells
***[[Hydropic Degeneration#Vacuolar Degeneration|Hydropic (vacuolar) degeneration]] of beta cells
***Acumultion of glycogen within the cytoplasm
***Acumultion of glycogen within the cytoplasm
***Develops in response to long-term overstimulation due to peripheral insulin resistance
***Develops in response to long-term overstimulation due to peripheral insulin resistance