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| #Eosinophilic '''ulcer''' which present as a well circumscribed, erythematous ulcer on the lip or oral mucosa of middle-aged cats | | #Eosinophilic '''ulcer''' which present as a well circumscribed, erythematous ulcer on the lip or oral mucosa of middle-aged cats |
− | #[[Eosinophilic Plaques|Eosinophilic '''plaques''']] which present as raised erythematous lesions on the skin of the medial thighs and abdomen | + | #Eosinophilic '''plaques''' which present as raised erythematous lesions on the skin of the medial thighs and abdomen |
| #Eosinophilic '''granuloma''' which present on the posterior aspect of the rear legs of young cats and also found on the [[Tongue - Anatomy & Physiology|tongue]], [[Hard Palate|hard palate]] and oral mucosa. | | #Eosinophilic '''granuloma''' which present on the posterior aspect of the rear legs of young cats and also found on the [[Tongue - Anatomy & Physiology|tongue]], [[Hard Palate|hard palate]] and oral mucosa. |
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| Eosinophilic granulomas of the '''oral cavity''' appear as '''yellow/pink raised linear lesions'''. They can also occur on the soft palate, or the base of the tongue. Cats with eosinophilic lesions of the mouth often have concurrent skin lesions. | | Eosinophilic granulomas of the '''oral cavity''' appear as '''yellow/pink raised linear lesions'''. They can also occur on the soft palate, or the base of the tongue. Cats with eosinophilic lesions of the mouth often have concurrent skin lesions. |
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− | The cause of feline eosinophilic granuloma is unknown but it has been associated with food and insect bite allergies, atopy, immunosuppression, bacterial and viral infections. | + | The cause of feline eosinophilic granuloma is unknown but it has been associated with food and insect bite allergies ([[:Category:Hypersensitivity|hypersensitivity]]), [[atopy]], immunosuppression, bacterial and viral infections. |
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| == Signalment == | | == Signalment == |
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| An ulcerated mass may be found at the base of the tongue or on the hard palate, the glossopalatine arches or anywhere else in the mouth as described above. On laboratory tests, a peripheral blood [[Eosinophilia|eosinophilia]] may be present. | | An ulcerated mass may be found at the base of the tongue or on the hard palate, the glossopalatine arches or anywhere else in the mouth as described above. On laboratory tests, a peripheral blood [[Eosinophilia|eosinophilia]] may be present. |
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| + | A deep biopsy specimen of the mass is required for a definitive diagnosis. |
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| == Pathology == | | == Pathology == |
| + | Histology reveals an eosinophilic tissue infiltrate and polymorphs are present. There is also an exaggerated eosinophilic response. |
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| + | Grossly, there are raised plaques, erythematous, pruritic, erosed or ulcerated areas. |
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− | A deep biopsy specimen of the mass is required for a definitive diagnosis. Histology reveals an eosinophilic tissue infiltrate and polymorphs are present. There is also an exaggerated eosinophilic response.
| + | Microscopically, acanthosis, spongiosis, erosions or ulceration, predominantly eosinophilic dermatitis, possibly areas of collagen degeneration can all be found. |
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| == Treatment == | | == Treatment == |