Changes

|linkpage =Integumentary System - Pathology

|linktext =Integumentary System

*Start as small [[Skin Glossary - Pathology|papules]] covered by brown [[Skin Glossary - Pathology|crusts]]

|maplink = Integumentary System (Content Map) - Pathology

*-> lesions join and spread -> umbilicated [[Skin Glossary - Pathology|plaques]] containing white centres with erythematous and scaly borders

|pagetype =Pathology

*Similar to [[Dermatophytosis|dermatophytosis]]

|sublink1 = Skin Congenital and Hereditary - Pathology

**Epidermal hyperplasia, [[Skin Glossary - Pathology|parakeratosis]], epidermal [[Skin Glossary - Pathology|pustules]] and superficial perivascular dermatitis

 

 

==Porcine Juvenile Pustular Psoriasiform Dermatitis (Pityriasis rosea)==

==Porcine Juvenile Pustular Psoriasiform Dermatitis (Pityriasis rosea)==

===General===

===General===

===Microscopic Lesions===

===Microscopic Lesions===

*Skin biopsy reveals superficial perivascular dermatitis with psoriasiform epidermal hyperplasia.   

*Skin biopsy reveals superficial perivascular dermatitis with psoriasiform epidermal hyperplasia.   

*The superficial dermis usually shows mild to moderate mucinous degeneration, and eosinophils and neutrophils are the predominant inflammatory cell types.   

*The superficial dermis usually shows mild to moderate mucinous degeneration, and eosinophils and [[Neutrophils|neutrophils]] are the predominant inflammatory cell types.   

*Intra-epidermal pustules containing eosinophils and neutrophils are prominent in early lesions.   

*Intra-epidermal pustules containing eosinophils and [[Neutrophils|neutrophils]] are prominent in early lesions.   

*Parakeratotic hyperkeratosis is usually prominent.

*Parakeratotic hyperkeratosis is usually prominent.

===Differential Diagnosis===

===Differential Diagnosis===

#Dermatophytosis ‑ (etio: Tr. mentagrophytes, M. canis, Tr. verrucosum var. discoides, M. nanum, Tr. rubrum) Ruled‑out due to lack of mycotic organisms.

#Dermatophytosis ‑ (etio: Tr. mentagrophytes, M. canis, Tr. verrucosum var. discoides, M. nanum, Tr. rubrum) Ruled‑out due to lack of mycotic organisms.

#[[Skin - infectious#Greasy pig disease|Exudative epidermitis (greasy pig disease)]] ‑ (''Staphylococcus hyicus'') Early lesions may appear as red plaques, but soon become exudative and ulcerated; R/O based on culture, lesion distribution, histopathology.

#[[Skin Infectious - Pathology#Greasy pig disease|Exudative epidermitis (greasy pig disease)]] ‑ (''Staphylococcus hyicus'') Early lesions may appear as red plaques, but soon become exudative and ulcerated; R/O based on culture, lesion distribution, histopathology.

#Dermatosis vegetans ‑ Systemic, erythematous maculopapular dermatitis caused by the inheritance of a autosomal recessive, semilethal factor.  Skin, coronary band and hoof lesions, giant cell pneumonia, fatal.

#Dermatosis vegetans ‑ Systemic, erythematous maculopapular dermatitis caused by the inheritance of a autosomal recessive, semilethal factor.  Skin, coronary band and hoof lesions, giant cell pneumonia, fatal.

#Swinepox ‑ Ballooning degeneration and intracytoplasmic inclusion bodies.

#Swinepox ‑ Ballooning degeneration and intracytoplasmic inclusion bodies.

Kate

Kate

::''IL-3 is involved... Vet Path (2007)  34: 45-43''

::''IL-3 is involved... Vet Path (2007)  34: 45-43''